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    Home > Active Ingredient News > Antitumor Therapy > European Radiology: Application of functional MRI in the characterization of benign and malignant parotid tumors

    European Radiology: Application of functional MRI in the characterization of benign and malignant parotid tumors

    • Last Update: 2022-01-08
    • Source: Internet
    • Author: User
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    Pleomorphic adenomas (PAs), Warthin tumors (WTs) and malignant tumors (MTs) are the most common types of parotid gland tumors
    .


    They account for 65%, 15-20%, and 15-30% of parotid gland tumors, respectively


    Magnetic resonance imaging (MRI) has been widely used to analyze the characteristics of parotid gland tumors
    .


    Although structural MRI can help describe the scope of the tumor, its diagnostic performance is limited by subjectivity and low reproducibility of structural MRI features


    diagnosis

    Without the need for contrast agents, 3D pCASL MRI can quantitatively calculate tumor blood flow (TBF) by measuring the proton magnetic susceptibility in arterial blood
    .


    Previous studies have proved that ASL and its derived TBF value are of great value in distinguishing parotid gland tumors


    Recently, published in the E uropean a journal Radiology study to assess the PLDs of 3D pCASL MRI performed parotid gland tumors characterized in terms of performance impact, and explore the best PLDs for differential diagnosis , for MR technology is widely used in clinical It paved the way and provided technical support for non-invasive and accurate preoperative evaluation of parotid gland tumors .

    Recently, published in the E uropean a journal Radiology study to assess the PLDs of 3D pCASL MRI performed parotid gland tumors characterized in terms of performance impact, and explore the best PLDs for differential diagnosis , for MR technology is widely used in clinical Opened the way and provided technical support for non-invasive and accurate preoperative assessment of parotid gland tumors

    This study included 58 patients with parotid gland tumors, including 33 patients with pleomorphic adenomas (PAs), 16 patients with Warthin's tumors (WTs), and 9 patients with malignant tumors (MTs)
    .


    Each patient underwent five 3D pCASL scans with PLDs of 1025 ms, 1525 ms, 2025 ms, 2525 ms, and 3025 ms


    With the increase of PLD, the TBF of PAs tends to gradually increase (p <0.


    001), while the TBF of WTs tends to increase slightly and then gradually decrease (p = 0.


    With the increase of PLD, the TBF of PAs tends to gradually increase (p <0.


    Figure PA (af), WT (jl) and MT (squamous cell carcinoma, mr) representative images
    .


    The first column shows the T2-weighted image of fat suppression (a, j, m)


    Figure PA (af), WT (jl) and MT (squamous cell carcinoma, mr) representative images


    This study shows that 3D pCASL is very valuable for characterizing PAs of WTs or MTs


    Original source :

    Hao Hu , Lu Chen , Liu-Ning Zhu ,et al .


    Hao Hu Lu Chen Liu-Ning Zhu ,et al 10.
    1007/s00330-021-08220-1 10.
    1007/s00330-021-08220-1 Leave a message here
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