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Medial temporal atrophy (MTA) is an important structural finding associated with Alzheimer's disease, but MTA can also be present in preclinical dementia
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In clinical practice, the interpretation of structural imaging is usually based on a radiologist's visual assessment
Medial temporal atrophy (MTA) is an important structural finding associated with Alzheimer's disease, but MTA can also be present in preclinical dementia
A recent European survey showed that 75% of institutions use VRS in clinical practice, of which 82% frequently use the White Matter Change Scale and 81% use the MTA Scale; other VRS are less common
A study published today in the journal European Radiology assessed the inter-modal consistency of MTA scores in a non-demented population and the accuracy between radiologists with different clinical experience , making it possible to standardize the process of MTA identification and assessment.
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Four raters (two junior radiologists and two senior neuroradiologists) scored MTA on CT and MRI scans using Scheltens' MTA scale
Forty-nine subjects with cognitive impairment (median age 72 years, 27% abnormal MTA) were included in the study
FIG prepared according Scheltens image MTA levels of 5 points example ) .
Each side is scored individually and an overall maximum score is given .
MTA 0=no atrophy, MTA 1=mild widening of the choroidal fissure, MTA 2=moderate widening of the choroidal fissure, mild widening of the temporal horn, and mildly decreased hippocampal height .
MTA 3 = severely widened choroidal fissure, moderately widened temporal horn, moderately decreased hippocampal height, MTA 4 = severely widened choroidal fissure, severely widened temporal horn, severely decreased hippocampal height .
Each side is scored individually and an overall maximum score is given .
MTA 0=no atrophy, MTA 1=mild widening of the choroidal fissure, MTA 2=moderate widening of the choroidal fissure, mild widening of the temporal horn, and mildly decreased hippocampal height .
MTA 3 = severely widened choroidal fissure, moderately widened temporal horn, moderately decreased hippocampal height, MTA 4 = severely widened choroidal fissure, severely widened temporal horn, severely decreased hippocampal height .
FIG prepared according Scheltens image MTA levels of 5 points example ) .
Each side is scored individually and an overall maximum score is given .
MTA 0=no atrophy, MTA 1=mild widening of the choroidal fissure, MTA 2=moderate widening of the choroidal fissure, mild widening of the temporal horn, and mildly decreased hippocampal height .
MTA 3 = severely widened choroidal fissure, moderately widened temporal horn, moderately decreased hippocampal height, MTA 4 = severely widened choroidal fissure, severely widened temporal horn, severely decreased hippocampal height .
The present study shows that when the Scheltens MTA scale was used to score MTA in non-demented populations, radiologists with different clinical experience reached sufficient agreement across different modalities with similar accuracy
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However, TPR differed between raters, possibly due to differences in scoring >
The present study shows that when the Scheltens MTA scale was used to score MTA in non-demented populations, radiologists with different clinical experience reached sufficient agreement across different modalities with similar accuracy
Original source :
Original source :Claes Håkansson , Ashkan Tamaddon , Henrik Andersson , et al.
Inter-modality assessment of medial temporal lobe atrophy in a non-demented population: application of a visual rating scale template across radiologists with varying clinical experience.
DOI: 10.
1007/s00330-021- 08177-1Claes Håkansson Ashkan Tamaddon Henrik Andersson 10.
1007/s00330-021-08177-1 Leave a message here