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European Radiology: In non-small cell lung cancer patients, we found another strong imaging prognostic marker

 Last Update: 2022-05-21
 Source: Internet
 Author: User

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granular cell tumor treatment

laryngeal squamous cell carcinoma

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According to statistics, lung cancer is one of the most common malignant tumors worldwide, accounting for the highest proportion of cancer deaths

Even with radical resection, 20% to 52% of stage I-III patients develop local recurrence or distant metastasis

Current guidelines recommend the use of [ ¹⁸ 18 F]FDG PET/CT for initial staging of all NSCLC patients

Classical PET variables, such as standardized uptake value (SUV)-based and volume-based variables, such as metabolic tumor volume (MTV) and lesion total glycolysis (TLG), have been identified as important prognostic factors in multiple studies , but The results are not consistent .

Recently, a study published in the journal European Radiology explored two new geometric variables, the normalized ^SUVpeak -to-centre distance ( nSCD ) and normalized The prognostic value of SUVmax-to-periphery distance (nSPD) and its correlation with classical metabolic parameters in NSCLC patients undergoing surgery .

This retrospective study enrolled patients with stage I-III NSCLC with baseline [ ¹⁸ 18 F]FDG PET/CT and obtained clinical, histopathological, and metabolic parameters for each patient .

A total of 173 patients were included in this study .

The results of this study demonstrate that nSCD and nSPD can be used as predictors of poor prognosis in NSCLC patients, outperforming classical PET-derived variables

Original source:

Germán Andrés Jiménez Londoño, Ana Maria García Vicente, Jesús J Bosque, et al.

Germán Andrés Jiménez Londoño, Ana Maria García Vicente, Jesús J Bosque, et al.
SUVmax to tumor perimeter distance: a robust radiomics prognostic biomarker in resectable non-small cell lung cancer patients.
DOI: 10.
1007/s00330-021-08523-3 SUVmax to tumor perimeter distance: a robust radiomics prognostic biomarker in resectable non-small cell lung cancer patients.
10.
1007/s00330-021-08523-3

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