European Radiology: Lineage plot of survival prognosis for triple-negative breast cancer

Triple-negative breast cancer (TNBC) is a type of breast cancer molecule that is negatively expressed by estrogen receptors (ER), progesterone receptors (PRs), and human epidermal growth factor receptor-2 (HER-2), accounting for approximately 15% to 20%

Studies have found that a number of clinicopathological factors, including age at diagnosis, positive status of axillary lymph nodes, lymphatic infiltration (LVI), and histological grade, are associated

At present, imaging techniques such as magnetic resonance imaging (MRI), molybdenum target (MG) and ultrasound (US) have been widely used in preoperative diagnostic techniques

Recently, a study published in the European Journal of Radiology predicted the clinicopathological and mammography features associated with TNBC survival prognosis, and developed and validated an effective predictive laminography model to assess TNBC prognosis, providing technical support

This study conducted a retrospective evaluation

A total of 636 TNBC patients were enrolled and divided into training cohorts (n=446) and validation cohorts (n=190

In this study, clinical factors including tumor size >2 cm, axillary lymphadenectomy, presence of LVI, absence of adjuvant postoperative chemotherapy, axillary lymph node load (≥ 4 positive lymph nodes), and malignant sonogram features are all associated

Original source:

Dan-Li Sheng,Xi-Gang Shen,Zhao-Ting Shi,et al.