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    Home > Biochemistry News > Biotechnology News > Evaluation of intra- and interspecific divergence of satellite DNA sequences by nucleotide frequency calculation and pairwise sequence comparison

    Evaluation of intra- and interspecific divergence of satellite DNA sequences by nucleotide frequency calculation and pairwise sequence comparison

    • Last Update: 2020-11-24
    • Source: Internet
    • Author: User
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    Satellite
    DNA
    sequences are known to be highly variable and to have been subjected to concerted evolution that homogenizes member sequences within species. We have analyzed the mode of evolution of satellite DNA sequences in four fishes from the genus
    Diplodus
    by calculating the nucleotide frequency of the sequence array and the phylogenetic distances between member sequences. Calculation of nucleotide frequency and pairwise sequence comparison enabled us to characterize the divergence among member sequences in this satellite DNA family. The results suggest that the evolutionary rate of satellite DNA in
    D. bellottii
    is about two-fold greater than the average of the other three fishes, and that the sequence homogenization event occurred in
    D. puntazzo
    more recently than in the others. The procedures described here are effective to characterize mode of evolution of satellite DNA.
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