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Obesity is considered to be one of the risk factors for at least 13 different types of cancer.
In order to determine the level of body fat, most epidemiological studies use body mass index (BMI, calculated as weight (kg)/height (m2)).
However, the relationship between the body fat composition of people with normal weight (BMI: 18.
5–24.
9 kg/m2) and the risk of cancer is currently unclear.
In this study, the researchers analyzed 149,928 normal-weight individuals (40-70 years old) who were included in the UK Biobank cohort between 2006 and 2010 to study obesity and breast cancer (postmenopausal), The correlation of the risk of endometrial cancer, ovarian cancer and colorectal cancer.
The results showed that all body fat indexes were positively correlated with the risk of invasive breast cancer after menopause.
The trunk fat mass index and waist circumference (WC) are positively correlated with the risk of endometrial cancer.
In men, the fat mass ratio of the thighs is positively correlated with the risk of colon cancer.
The body fat index of women has nothing to do with the risk of ovarian cancer or colorectal cancer.
In summary, the relevant characteristics of the participants of the British Biobank, the results of the study show that the relevant fat composition data in the normal weight population based on BMI shows a correlation with an increased risk of obesity-related cancers.
Original source: Arthur, RS, Dannenberg, AJ, Kim, M.
et al.
The association of body fat composition with risk of breast, endometrial, ovarian and colorectal cancers among normal weight participants in the UK Biobank.
Br J Cancer (15 March 2021).
In order to determine the level of body fat, most epidemiological studies use body mass index (BMI, calculated as weight (kg)/height (m2)).
However, the relationship between the body fat composition of people with normal weight (BMI: 18.
5–24.
9 kg/m2) and the risk of cancer is currently unclear.
In this study, the researchers analyzed 149,928 normal-weight individuals (40-70 years old) who were included in the UK Biobank cohort between 2006 and 2010 to study obesity and breast cancer (postmenopausal), The correlation of the risk of endometrial cancer, ovarian cancer and colorectal cancer.
The results showed that all body fat indexes were positively correlated with the risk of invasive breast cancer after menopause.
The trunk fat mass index and waist circumference (WC) are positively correlated with the risk of endometrial cancer.
In men, the fat mass ratio of the thighs is positively correlated with the risk of colon cancer.
The body fat index of women has nothing to do with the risk of ovarian cancer or colorectal cancer.
In summary, the relevant characteristics of the participants of the British Biobank, the results of the study show that the relevant fat composition data in the normal weight population based on BMI shows a correlation with an increased risk of obesity-related cancers.
Original source: Arthur, RS, Dannenberg, AJ, Kim, M.
et al.
The association of body fat composition with risk of breast, endometrial, ovarian and colorectal cancers among normal weight participants in the UK Biobank.
Br J Cancer (15 March 2021).
