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    Home > Medical News > Latest Medical News > [exclusive] large varieties that have escaped the national catalogue of auxiliary drugs for the time being

    [exclusive] large varieties that have escaped the national catalogue of auxiliary drugs for the time being

    • Last Update: 2019-02-25
    • Source: Internet
    • Author: User
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    At the end of 2018, the national health and Health Commission issued the notice on the management of clinical application of auxiliary drugs, requiring all provincial health and health administrative departments to organize medical institutions at or above the second level within their jurisdiction to rank the auxiliary drugs in their common names and form the catalogue of auxiliary drugs according to the annual amount of use (December 1, 2017 to November 30, 2018), which is listed on the Report to the provincial health administrative department In principle, there are no less than 20 types of auxiliary drugs in each medical institution Each provincial health and health administration department shall summarize the list of auxiliary drugs reported by the medical institutions within its jurisdiction, and report the information of the first 20 varieties to the national health and Health Commission in the order of common name and total amount of use The national health and Health Commission formulates and publishes a national catalogue of auxiliary drugs As soon as the red head document is published, it will once again push the auxiliary drugs, which are already under key monitoring, to the forefront of the wave The insiders predict that this will have a significant impact on the pattern of the pharmaceutical market According to the database of drug intelligence assisted and key monitored drugs, the author sorted out the drugs with the highest frequency and ranking in the "directory of assisted drugs" or "directory of key monitored drugs" published by all parts of the country in recent years, and according to the requirements of the notice on doing a good job in clinical application management of assisted drugs, calculated the average amount of use in 2015-2017 (unit: Hundred million yuan) from more to less, the "national auxiliary drug prediction catalogue" of pharmaceutical intelligence has been formed from the perspective of the third party (see the table below) Table 1: Pharmaceutical intelligence "national auxiliary drug prediction catalogue" The author compares the "national auxilliary drug use prediction catalogue" of Yaozhi with the recently circulated "letter on Soliciting Opinions of the notice on carrying out drug use monitoring and clinical comprehensive evaluation (Draft for comments)" (hereinafter referred to as the "draft catalogue") drafted by the Department of drug administration of the National Health Commission, and finds 52 varieties in the "national auxilliary drug use prediction catalogue" of Yaozhi At the same time, it is also in the "comment list"; another 29 varieties are not in the comment list The prediction results also verify the reliability of "opinion list" circulated on the Internet 29 non "comment list" varieties are likely to escape from the national auxiliary drug list this time, with a high probability of appearing in the second batch of national auxiliary drug list (see Table 2 and table 3 for 52 auxiliary drug forecast directories already in the draft and 29 auxiliary drug forecast directories not in the draft) Table 2: 52 list of predicted auxiliary drugs in the draft Table 3: 29 list of predicted auxiliary drugs not in the draft what is the definition of auxiliary drugs? All along, the list of auxiliary drugs in each province is endless, but there is no clear official definition and analysis The following collection of some provinces and cities about the clear definition of adjuvant: Xinjiang: in the drug manual or clinical diagnosis and treatment guide, the role of a certain disease is clearly defined as adjuvant drugs This kind of medicine alone can not achieve the purpose of treating the disease Auxiliary drugs are relative to therapeutic drugs, so the hospital formulates the catalogue of auxiliary drugs according to the pharmacological effect and characteristics of drugs Inner Mongolia: drugs that help to increase the effect of main therapeutic drugs or increase their efficacy and reduce side effects by influencing the absorption, mechanism and metabolism of main therapeutic drugs; or drugs that help to prevent and treat diseases or disorders of body functions Fujian: the drug manual specifies the clinical path of "adjuvant treatment" or issued by the national health and Family Planning Commission, as well as the clinical guidelines issued by the first level (first class) academic association such as the Chinese Medical Association, and the drugs for adjuvant treatment mentioned in the consensus of experts PubMed, the National Library of medicine of the United States, explained the auxiliary drugs in mesh in 2011, and explained the auxiliary drugs in some monographs, such as clinical medication instructions and newly edited pharmacology Combined with the indications and pharmacological effects indicated in the drug manuals, the auxiliary drugs were defined as: helping to increase the effect of the main therapeutic drugs or influencing the absorption and mechanism of the main therapeutic drugs A drug produced or metabolized to increase its efficacy; or a drug that, on the basis of conventional treatment of a disease, contributes to the prevention and treatment of a disease or dysfunction It is often used to prevent or treat major diseases such as tumor, liver disease and cardiovascular and cerebrovascular diseases Generally speaking, all regions and medical institutions list the drugs that are used in the hospital and clinical departments as auxiliary drugs The accuracy of this approach remains to be examined The problem is that the same drug will have different definitions in different disease areas, and the essence is whether it can meet the needs of rational drug use Hu Xin, director of Pharmacy Department of Beijing hospital, introduced several principles to be followed when selecting auxiliary drugs in Beijing hospital on January 23, when the country has not clearly formulated the selection criteria of auxiliary drugs: 1 The amount of drugs used in hospitals ranked top 100; 2 There is no guide to recommend; 3 The clinical evidence is insufficient; 4 It is applicable to a variety of diseases; 5 It is not included in the Chinese Pharmacopoeia First of all, what is the difference between auxiliary drug use and key monitoring drug use? In fact, there is no substantive difference between the two The formulation of auxiliary drugs is to focus on monitoring to see whether it meets the requirements of rational use of drugs It just means that in response to the national promotion of the scientific management level of auxiliary drugs, different regions put forward different names, and even some regions directly call the directory of key monitoring of auxiliary drugs Second, auxiliary drug is the drug for auxiliary treatment The drug for auxiliary treatment is not an invalid drug or a universal drug It has specific indications This problem must be clear: it does not mean that the auxiliary drug is not used Third, even after the introduction of the national catalogue of auxiliary drugs, it does not mean that the drugs included in the catalogue can not be used, but only focus on strengthening the management of rational drug use, and more standardized and rational use Statement: this opinion only represents the author, not the position of yaozhi.com, welcome to exchange and supplement in the message area; if you need to reprint, please be sure to indicate the author and source of the article.
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