Experimental method of ampule breaking force tester

Ampoule bottle is a small sealed glass container used to hold liquid medicine It is often used to store drugs for injection, vaccines, serum, etc with a capacity of 1-25ml The breaking force of ampoule bottle is a key index for manufacturers With the official promulgation and implementation of 2015 version of drug packaging materials standard, the detection of various drug packaging materials is also highly valued Ampoule bottle is a commonly used packaging form of medicine packaging Gb2637-1995, ybb00332002-2015 and other national standards and drug packaging materials standards have made clear provisions on the breaking force of ampoule Mark the bottleneck of ampoule bottle When pressure is applied, the bottleneck will break to extract the liquid medicine The purpose of this paper is to discuss the testing requirements and methods of breaking force at the bottleneck of ampule bottle: set a distance between two metal supports to apply force between two metal supports which are 90 ° to the central axis of the ampule under test Use the ampule breaking force tester to apply force until the ampule breaks, and record the breaking force value Note: when the breaking force of the ampule is easy to be broken at the test point, the force application part in the device should be positioned in the middle of the score (the score is downward), otherwise the breaking force will increase After the ampule is broken, the cross-section shall be flat (the cross-section shall be free of sharp bulges, notches and cracks longer than the shoulder) Among them, the standard instrument for measuring the breaking force of ampoules should have the following characteristics: the precision is 0.1N; the test speed is 10 mm / min; the measuring range of force is 0-200n; the ampoule breaking force tester independently developed and produced by Jinan Sanquan Zhongshi Zdy-01, the resolution of the instrument is 0.01, for the commonly used 1ml, 2ml, 5ml, 10ml, 20ml ampoule bottles, the corresponding fixture is customized; the instrument adopts foreign well-known sensors, with high precision, adjustable instrument speed, 1-500mm / min stepless speed regulation; the full-automatic control mode is adopted, and the large liquid crystal screen displays the whole test process curve, which is convenient for user operation and greatly improves the test data results 。 By measuring the breaking force of ampoules, we can help ampoule manufacturers and pharmaceutical companies to monitor the packaging quality and adjust and optimize the production process, so as to avoid product quality problems caused by packaging quality.