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    Home > Active Ingredient News > Antitumor Therapy > Express extended the survival time of advanced lung cancer by two times, and the positive results of the innovative spot cancer vaccine were announced

    Express extended the survival time of advanced lung cancer by two times, and the positive results of the innovative spot cancer vaccine were announced

    • Last Update: 2022-09-21
    • Source: Internet
    • Author: User
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    ▎ WuXi AppTec content team editor

    Gritstone bio recently announced the results



    The SLATE project is a cancer vaccine immunotherapy that uses engineered methods to deliver tumor neoantigens into patients to stimulate A T cell response (especially CD8+ toxin T cells) to attack tumors



    The purpose of this Phase 1/2 trial is to test the safety, immunogenicity and early clinical efficacy



    Image credit: 123RF


    Data analysis showed that SLATE v1 showed consistent and strong immunogenicity with SLATE-KRAS vaccine, and the ex vivo enzyme-linked immune spot test (ELISpot) showed that 31% and 55% of patients treated with SLATE v1 and SLATE-KRAS triggered KRAS-specific CD8+ T cells



    This therapy also shows good safety and tolerability, and most of the treatment-related adverse reactions are of class



    "We are encouraged




    WuXi AppTec provides integrated, end-to-end new drug development and production services to the global biopharmaceutical industry, covering chemical drug development and production, biological research, preclinical and clinical trial development, cell and gene therapy research and development, testing and production


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