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    Home > Medical News > Medical World News > Extending life to improve health Scientists have found key molecules in the online granules.

    Extending life to improve health Scientists have found key molecules in the online granules.

    • Last Update: 2020-07-24
    • Source: Internet
    • Author: User
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    A team of researchers from the University of Southern California (USC) recently published a paper in the journal Aging describing the role of a mitochondrial peptide molecule called humanin in regulating life"Humanin has long been known to prevent many aging-related diseasesBut this is the first time we know that it can extend lifeProfessor Pinchas Cohen, who led the study, saidhumanin is more than human mitochondria, although the name has "human"In fact, the presence of such molecules in mitochondria throughout the animal kingdom suggests that they may be somewhat conservative in evolutionTo understand the role of humanin, the researchers examined human levels in humans and in a variety of animal modelshas been found in the past that in many animal species, humanlevel levels decline as they ageThe study suggests that in many older animals, humanin levels remain at a high levelFor example, naked molerats, who look strange but live very long, have a very slow decline in humanin levels during their nearly 30-year-old "rat life"In contrast, mice lost 40% of humanin in the 18 months of life! Primate animals, such as rhesus monkeys, also have significantly lower levels of humanin in their bodies between the ages of 19 and 25interesting, the researchers found the children of 18 centenarians and compared them to the descendants of 19 other non-centenariansThe comparison found that the former's human level could indeed be maintained at a very high levelAnd they do live longer, what happens when human levels are artificially increased? The scientists did a test in the online wormThey found that increasing the expression of humanin was enough to extend the life of nematodesIn mice, the additional humanin improved their metabolism overall, although they did not significantly extend their life span And whether nematodes or mice, they become thinner researchers noted in an official press release that while humanin appears to extend life and improve health, it is not without its costs -- these long-lived nematodes have fewer offspring In the past, scientists have observed similar phenomena in long-lived humans, the paper notes " balance between longevity and reproduction may be evolutionaryly conservative It depends on whether we want to use energy to breed more offspring, or whether we use energy to maintain the health of individuals for possible future reproduction Evolutionaryly, the purpose of life is to reproduce If you can't reproduce for a while, you should live as long as possible And the 'side effect' is longevity Professor Kelvin Yen, the first author of the study, said .
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