Extracellular substring proteins that attract deadly toxins.

Scientists at UCL, University College London, have discovered the mechanism by which tetrave nerve toxin enters nerve cells, blocking the process and treating tetrave.
study, published this week in the journal Science, also suggests that this path path can be developed into a new drug delivery system that better treats neurological disorders, such as motor neurone disease and peripheral neuropathy.
is a disease caused by tecobacteria invading human wounds, growing and breeding, producing toxins, and the mortality rate is higher.
despite the presence of an effective teyemics vaccine, targeted treatments have not been developed and it is not clear how toxins enter the nervous system.
researchers found in mice that nidogen, which covers the surface of cells, is the key to the entry of tetrabuster neurotoxins into the nervous system.
tetravenous neurotoxins attach to nest proteins on the surface of nerve cells, "shuttle" into them, and then spread there to poison the entire nervous system.
protein is an extracellular substrine protein that participates in a variety of protein interoperability and maintains the integrity of many tissues, of which the nervous system is one.
"nest proteins cover nerve cells and attract tetra bruised nerve toxins to gather there," said Kinga Bercsenyi, lead author of the paper.
" motor neurons are surrounded by high levels of nest proteins, so tetrades nerve toxins aggregated there in large numbers, with the result that low amounts of toxins can also be highly toxic.
" researchers point out that people can also use nest proteins to send drugs into the nervous system in the same way as tethybus toxins.
this is a bit like virotherapy, an emerging area that mainly uses modified viruses to transport drugs to their destinations.
"Treating neuropathy is challenging, and if it's effective in sending drugs into neurons, it's half as successful," said Professor Giampietro Schiavo, who led the study.
now we want to simulate the entry mechanism of tetrane neurotoxins and send therapeutic drugs into motor neurons, " he said.
study will help people better understand how natural mating bodies and harmful substances enter the nervous system.
study shows that the substrings around neurons play a crucial role in this process.
can be used to develop new drug delivery strategies that concentrate the drug in the right area (motor neurons) for low-volume, high-efficiency results and reduced side effects.
source: Microbial technology applications.