"Father of Lupus in China", Professor Chen Shunle, one of the founders of rheumatology in China, has died

Professor Chen Shunle (right) and Professor Huang Mingxin today (January 23) morning, Shanghai Jiaobi University School of Medicine affiliated Renji Hospital news: One of the founders of rheumatology in China, a well-known rheumatologist, Renji Hospital tenured professor, Shanghai Rheumatology Research Institute Honorary Director Professor Chen Shunle, due to ineffective medical treatment, January 23, 2021 at 0:30 in Renji Hospital died at the age of 89.
Chen Shunle was born in February 1932, chief physician, professor, doctoral tutor, director of Shanghai Rheumatology Clinical Medical Center, honorary director of Shanghai Rheumatology Research Institute, tenured professor of Renji Hospital affiliated with Shanghai Jiao Jiao university medical school, director of rheumatology and immunology (Shanghai), honorary member of the Australian Rheumatology Society, "LUPUS" "Clinical Rheumatology" and other English-language magazine editorial board members, has served as the Chinese Medical Association rheumatology Society Vice Chairman, Vice President of Shanghai Medical Association, Chairman of the Rheumatology Branch of Shanghai Medical Association, Chairman of the Asia-Pacific Rheumatology Alliance, Editor-in-Chief of arthritis and Rheumatism (Chinese edition) of the famous American journal rheumatology, Executive Vice President of Shanghai Medicine, President of the Alliance of The Asia-Pacific Rheumatology Society (2000-2004), Member of the National Natural Science Foundation and the Medical Fund of the Ministry of Health, Vice-Chairman of the Chinese Journal of Rheumatology. Executive Vice Editor of Shanghai Medical Journal, Editorial Board of Shanghai Journal of Immunology and ALAR Journal.
Professor Chen Shunle is the founder of The Rheumatology Department of Renji Hospital, affiliated with Shanghai Jiaoba University School of Medicine, and the Shanghai Institute of Rheumatology, which presides over the establishment of the largest genetic database of the core family of lupus in China, and the creation of a combination of PMC small-dose immunosuppressant therapy to improve efficacy while reducing side effects.
his team worked with obstetrics and gynecology to break the birth exclusion zone, making lupus a mother no longer a luxury.
he has made outstanding contributions to the experimental and clinical research of rheumatology in China, especially systemic lupus erythematosus, and is one of the main founders of rheumatology in China.
has conducted a series of epidemiological surveys of rheumatoid diseases in China, including systemic lupus erythematosus, osteoarthritis, gyro and COPCORD, filled the gaps in China, and pioneered research including autoigen antibodies, autoimmune rheumatoid disease treatment strategies and rheumatism-related genes, which has strongly promoted the development of rheumatism in China.
issues have won the National Natural Science Foundation, the Ministry of Health science and technology progress and the Shanghai Science and Technology Progress Award.
Professor Chen Shunle received special allowances from the State Council and advanced workers from the Ministry of Health in 1995, and was awarded honorary titles such as "Shanghai Model Worker", "Lifelong Professor of Renji Hospital affiliated with Shanghai Jiaoyu University School of Medicine" and "Shanghai Yucai Award" in 2001.
was awarded the honorary title of "Master of Rheumatology" by the American Rheumatology Institute in 2004, becoming the first recipient of this honor in China and Asia.
He presided over the systematic lupus erythematosus (SLE) research topic has won the National Natural Science Foundation, the Ministry of Health, the Ministry of Education and the Shanghai Science and Technology Progress Award, in 2009 won the second prize of the National Science and Technology Progress Award, published a SLE monograph and the Ministry of Health "11th Five-Year Plan" national medical graduate planning teaching materials 1.
Professor Chen Shunle pays attention to talent training, has hosted many domestic and foreign academic conferences, especially the "8th International Lupus Conference" successfully held, established the Renji Hospital rheumatology discipline in the field of international lupus research academic status, but also promote the development of Rheumatology in China and the entire Asia-Pacific region, for the vast number of lupus patients to bring hope.
Professor Chen Shunle has been praised by his international peers as "the father of lupus in China" and has been awarded the master title of the American Rheumatology Institute, the Asia-Pacific Rheumatology Alliance Master Award, the "Outstanding Contribution Award" of the Chinese Rheumatology Society, the advanced workers of the Ministry of Health, the honorary title of Shanghai labor model, the Shanghai Yucai Award, the top ten workers inventors in Shanghai and the title of scientific and technological innovation of the top ten workers in Shanghai, and many other honors, enjoy the special allowance of the State Council.
Professor Chen Shunle, touched the hearts of future generations, Renji Hospital rheumatologist Li Jia wrote a recollection: take a long shot Sirius to mourn our country's famous rheumatologist Professor Chen Shunle he is the pioneer of Renji rheumatism he is China's rheumatoid guide he is a world-renowned ACR master, APLAR master he is China's "father of SLE" he presided over the development of China's first SLE diagnostic standards he formed the rheumatology department's earliest MDT he built the rheumatology department's earliest database he led the rheumatology department's earliest genetics found that he established the country's first rheumatology institute's first "lupus health club" ... When he meets, he is always smiling and shaking hands when the elders are confused, he is often carefully taught when the mentor is ill, he is always trustworthy doctor He is the pioneer, builder, nurturer he is a life-long concern about the old father "healthy, competition, Pretty" is his greatest dream in the world from "clone choice" to Renji rheumavigic Huangpu River, Shandong Zhonglu 145, Renji Hospital site, there is a brick-red building after more than 80 years of wind and rain, Chen Shunle worked here for half a century.
even in the last days of his life, he was concerned about the future of Bengji rheummatoid.
back in time.
office case, like a hill, Chen Shunle turned out a handwritten translation: "The autoimmune process and the disease of autoimmune disease", the cover reads "Chen Shunle translated in the summer of 1963."
his thoughts are back to the spring of 50 years ago, when Australian scholar Macfarlane Burnet creatively proposed the "clone option theory" and won the Nobel Prize in medicine for his work on autoimmune diseases.
Huang Mingxin and Professor Jiang Shaoji hand-handedly handed over the English literature to Chen Shunle, a 70-page booklet that pinned the vision and fervent hopes of two medical predecessors and sowed the seeds of Renji rheumatism.
In 1979, the Shanghai Institute of Immunology was established, immunologist Professor Yu He was the first director, Huang Ming was the new second director, Jiang Shaoji was the deputy director and director of the Clinical Immunology Research Office, Chen Shunle was the deputy director and presided over the daily work, and soon, the discipline of rheumatology based on the Clinical Immunology Research Office was established.
, there were only three staff members and eight beds.
this is the earliest rheumatology department in China.
Chen Shunle chose systemic lupus erythematosus (SLE) as the main direction of the rheumatology department, which is an autoimmune disease that can affect multiple organs throughout the body, with complex lesions, difficulty in treatment and extremely high mortality.
there was no epidemiological investigation of the incidence of SLE in China at that time, and it was generally believed that the prevalence of lupus in Chinese was high and serious.
Chen Shunle used the knowledge he learned at the University of Melbourne, Australia, to establish a laboratory testing platform for autoimmune diseases, and through independent research and development, for the first time in China to establish a pumpable nuclear antigen (ENA) antibody spectrum and anti-heart phospholipid antibody detection technology, so that the diagnosis of SLE is well-founded.
Then, using these techniques, he conducted a large-scale epidemiological survey of 32,668 Textile Workers in Shanghai and found that the prevalence rate of SLE in China was 70 per 100,000 and 113 per 100,000 in women.
the results were written into the textbooks of Chinese medical students and caught the world's eye, and Professor Bevra Ham, president of the American Rheumatology Society, warmly invited Chen Shunle to give an academic report, and has since become a lifelong friend.
chen Shunle found in the treatment, although high-dose hormones are beneficial to control the disease, but it brings many side effects, drug-induced complications greatly affect the quality of life of patients.
After thinking and demonstrating, he proposed a "PMC" treatment plan, using a small dose of hormones combined with methotrexate and chloroquine to treat patients with mild and moderate lupus without visceral tiredness, which became a classic treatment for SLE patients, greatly improving survival rates and allowing many patients to live and work normally.
At the same time, Chen Shunle looked around Shanghai, he noticed that those who have a single rheumatism treatment tradition of the hospital, he came out of Renji, Andi Newport location hospital cooperative research systemic stymied disease, and Guanghua Hospital cooperative research rheumatoid arthritis, he and colleague Gu Yueying involved in these hospitals outpatient, room and difficult case discussion, but also the foreign rheumatism field progress introduced to these hospitals, invited foreign experts to do lectures and business exchanges.
these cooperations, opened up his horizons and raised the level of diagnosis and treatment of rheumatology in Shanghai.
the places that left his footprints and recorded the trajectory of the development of rheumatology in China.
since 1982, he has been holding rheumatology training courses in Shanghai.
Since rheumatology is still in its infancy and there are no teachers, he invites experts in various fields to teach about rheumatology in his field, orthopaedic professors to lecture on the structure and function of joints, and pathology professors to lecture on the pathology of connective tissue disease. Change, professor of immunology on autoimmunity of rheumatology, professor of radiology on X-ray diagnosis, professor of dermatology on rheumatology-related skin damage, professor of ophthalmology about the eye performance of rheumatism, professor of physiotherapy about the rehabilitation of arthritis ... In just a few days, 26 experts from Huang Mingxin, Jiang Shaoji, Chen Shunle, Shi Shouyi, Chen Renyi, Zhang Petit, Wang Yongling, Jiang Peiling, Su Lide, Guo Wenzheng, more than a dozen research institutes and hospitals appeared, opening the door to the enlightenment and popularization of rheumatology in Shanghai.
, rheumatoid disciplines have been established in various hospitals.
, he held several national courses to promote the laboratory diagnosis of rheumatology technology, improve the national level of rheumatology diagnosis.
In 1988, he developed the diagnostic standards of SLE in China, which were verified by the relevant departments of 27 medical units nationwide, and confirmed that the ARA standard in the United States was more conducive to the early diagnosis of SLE than the 1982 ARA standard, which was adopted as a national standard and included in the textbooks of medical colleges and universities.
Chen Shunle's vision is not only in the clinical, he is well aware of the progress of basic research on the clinical giant role, in the 1990s, when molecular genetics research just set off a wave in the international community, he spent a lot of money to introduce equipment, and trained a group of molecular genetics research professionals, so that Renji feng shui in this field into the international forefront.
and his research team became the earliest and most famous team in the country to study rheumatology genetics.
1999, the epidemiological survey of Renji Rheumatology Department showed that the 10-year survival rate of SLE patients increased from 25% in the 1960s to 84%, and the 18-year survival rate reached 70%, which has leapt to the international advanced level.
2000, Renji established the country's first modern rheumatology research institute.
2002, Renji established the Shanghai Rheumatology Clinical Medical Center.
2005, Systemic Lupus, the first SLE monograph in the Asia-Pacific region.
2007, Renji established an integrated technology platform for clinical transformation of autoimmune diseases.
January 11, 2010, Chen Shunle walked into the Great Hall of the People and received the 14th Science and Technology Award Certificate from the national leaders - "The Pathogenesis and Clinical Treatment Technology of Systemic Lupus" won the second prize of the 2009 National Science and Technology Progress Award.
"click" to record the exciting moment, this photo, also hung in his office, as a spur and inspiration to himself.
"You have truly established a world-class, won the respect of the global peer rheumatology discipline."
" On the occasion of the 30th anniversary of Renzi Rheumatology, Professor Eng M Tan of the Scripps Institute in California, USA, who is known as the "father of autoantibodies", wrote in a congratulatory letter.
And Chen Shunle, has also become the soul of the international rheumatology field, as a Chinese, he was first elected president of the Asia-Pacific Rheumatology Society Alliance, was awarded the "ACR Master" honorary title by the American Rheumatology Society, won the Asia-Pacific Rheumatology Alliance "Master" Award.
What he has is not only honor and certificate, not far from thousands of miles of patients, rheumatology clinics and wards bustling, proved his efforts and efforts, rheumatoid field "South has benevolence", but also with the reputation of the people spread all over the world.
flowers in full bloom garden spring 2003, a noun came out - GROPEC cooperative organization.
this acronym represents the six departments of Renji Hospital: Gynecology, Radiology, Orthopaedics, Pediatrics, Endocrinology and Cardiology, the most closely linked departments of rheumatology, and Chen Shunle, who formed the organization in the hope of promoting rheumatology through interdisciplinary collaboration.
at Chen Shunle's clinic, he often encounters the same question as a female SLE patient: "Can I get pregnant?" Looking at the patient's nervous and expecting eyes, Chen Shunle always smiled and said: "Of course, but when pregnant, to listen to me."
" patients relieved, but they do not know, in order to this commitment, the old doctor has been white how much to pay.
In the treatment of lupus, pregnancy is considered to aggravate the disease, so traditionally doctors generally do not recommend the patient to give birth, and in China, a country with a traditional sense of "no later" traditional consciousness, infertability is more heavy on the patient's mental burden and pain.
rheumatology and obstetrics and gynecology join hands, after continuous attempts and efforts, finally achieved a breakthrough of zero - in 1992, the first SLE patient's baby fell to the ground, since then, SLE is no longer a no-go zone for fertility.
chen Shunle summarized the pre-pregnancy disease relief standards for SLE patients to provide reference for clinicians' treatment decisions.
weekly radiology department in rheumatology held difficult case reading sessions, orthopaedics actively participate in the surgical treatment of arthritis patients at the end of the period, cardiology to join rheumatology-related pulmonary hypertension diagnosis and research ... These collaborations have enabled gropec sections to grow rapidly.
Department of Radiology published the country's first rheumatology imaging book;