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    Home > Medical News > Medical Research Articles > FDA approves new oral fumarate drug Vumerity for treatment of recurrent multiple sclerosis

    FDA approves new oral fumarate drug Vumerity for treatment of recurrent multiple sclerosis

    • Last Update: 2020-06-07
    • Source: Internet
    • Author: User
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    today, http://
    the u.SFDA(http://officially approved its new oral fumaratedrug(http://) for the treatment of recurrent multiple sclerosis (MS) patients,announcedVumerity is a precursor to oral fumarateIt can be quickly converted into methylene sulprates in the bodyMomaracid monomethylesters can reduce damage from oxidative stress by activating a transcription factor called Nrf2This approval is based on Vumerity's performance in two Phase 3 clinicaltrial(http://In a trial called EVOLVE-MS-2, the proportion of patients who withdrew from the trial because of adverse events (AE) was 1.6% in the Vumerity treatment group, compared with 6.0% in the active control group of tecfidera, an approved metforma teracutane therapy , the proportion of patients who withdrew from the trial due to adverse events in the gastrointestinal (GI) was 0.8% in the treatment group and 4.8% in the active control group Another mid-term study, called THE EVOLVE-MS-1 trial, showed that the proportion of patients who withdrew from the trial because of all AE was 6.3 percent Of these, the proportion of patients who withdrew from the trial due to GI adverse events was less than 1%
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