Ferulic acid

Ferulic acid

Ferulic acid

【Structural formula】

[Molecular formula and molecular weight] C ₁₀ H ₁₀ O ₄ ; 194.
18

[Source] Umbelliferae Angelica sinensis (Oliv.
) Diels dry roots
.

【Properties】Colorless needle-like crystals
.

This product is soluble in water, ethanol , ethyl acetate ; ether soluble, petroleum ether , benzene insoluble

Melting point: 170~172℃
.

【Purity Check】

TLC

1.
Thin layer plate silica gel G

Developing agent benzene- glacial acetic acid -methanol (30:1:3)

Check under UV lamp (366nm)

2.
Thin layer plate silica gel G

Developing agent benzene-ethyl formate-formic acid (6:3.
5:0.
5)

Check under UV lamp (366nm)

High performance liquid chromatography

Chromatographic column Agilent SB C ₁₈ , 10um (4.
6mm×250mm)

Mobile phase methanol-1% glacial acetic acid (40:60) lml/min

Detection wavelength 316nm

【Structural identification】314,289,216
.

3437 (-OH), 3016 (-Ar), 1692 (C=O), 1620, 1600, 1517, 1433, 1277 (CO), 1205, 1177, 1036, 853, 804
.

ESI-MS m/z: 194[M+H] ⁺
.

¹ H-NMR (CD ₃ OD) δ: 3.
87 (3H, s, 3-OCH ₃ ), 4.
89 (1H, s, 4-OH), 6.
28 (1H, d, J=15.
76 Hz, 9-H), 6.
79(1H,d,J=8.
24Hz,5-H), 7.
03(1H,d,J=8.
24Hz,6-H), 7.
15(1H,d,J=8.
4Hz,2-H), 7.
57( 1H, d, J=15.
76Hz, 10-H)
.

¹³ C-NMR (CD ₃ OD) δ: 128.
25(C-1), 116.
93(C-2), 150.
93(C-3), 149.
79(C-4), 116.
35(C-5), 112.
13(C- 6), 56.
89 (C-7), 147.
42 (C-8), 124.
46 (C-9), 171.
47 (C-10)
.

【Storage】Dry and airtight
.

Related link: Bai Qiu Li Alcohol