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If you are destined to be injured, try to get hurt during the day.
because wounds appear to heal twice as fast during the day as they appear at night.
Nathaniel Hoyle of the Molecular Biology Laboratory at the University of Cambridge in the United Kingdom and his team found that genes in a particular skin cell turn on or off day and night, and they began to study how time of day affects healing.
these skin cells, called fibroblasts, help heal wounds after the skin is wounded, and some genes whose activity changes over time over the course of the day help control the process.
team surprised by this day and night change in gene activity and decided to analyse data collected by a special burn unit at the University of Manchester.
they found that, on average, wounds healed much faster during the day - only 17 days, compared with 28 days for burning-like burns that occurred at night. "We found that the extent of people's healing depends on the time of the injury, "
.
," Hoyle said, "the rate of healing during the day is 60 percent faster."
", when the skin has a cut, the fibroblasts rush to the wound, secreting a matrix that helps skin cells move to situ, grow, and heal the wound.
before studying burn data, the team first found in mouse tissue experiments that fibroblasts were twice as fast as they did when they were awake during normal waking than they did during sleep to reach a new wound quickly.
this seems to be because about 30 of the genes are more active when they are awake.
these genes help control the actin, a protein used by fibroid cells to move.
Hoyle's team believe that the rate of healing may be related to the circadian rhythms of mammals, as people are more likely to be injured during daytime activities.
he said the findings may be beneficial to medicine.
, for example, that if the drug is allowed to "induce" the injured area into a "daytime" state, they may heal more quickly.
" this study adds more evidence of the importance of medical time and circadian rhythms. "The question is how we use this knowledge and whether it can change clinical practice and help patients," says Derek-Jan Dijk of the University of Surrey in the UK,
.
"