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On March 25 ,
With the increasing prosperity of the global economy, obesity has become one of the health problems that endanger the world.
In order to analyze the potential downstream neural circuit mechanism of histaminergic nerves in feeding behavior, the research group constructed HDC-CreERT2 mice and used whole-brain microscopic optical section tomography ( fMOST ) to perform whole-brain three-dimensional imaging of histaminergic nerve projections After reconstruction, it was found that the density of histaminergic nerve fibers in the medial septum ( MS ) was high .
The role of histamine in regulating feeding behavior has long been considered to be mediated by H1 receptors, while H2 receptors are not involved in the regulation of feeding behavior .
