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    Home > Active Ingredient News > Drugs Articles > Free supply of 2019 ncov N protein expression strain

    Free supply of 2019 ncov N protein expression strain

    • Last Update: 2020-02-02
    • Source: Internet
    • Author: User
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    Novel coronavirus (novel coronavirus) novel coronavirus (2019-nCoV) was officially named as the 2019 coronavirus (NCBI) in Wuhan in January 12, 2020 The complete sequence of the new coronavirus genome was submitted to NCBI public health clinical center of Fudan University in January 10th In GenBank database, 28274-29533 "n" genes can produce nucleocapsid protein (N protein) Referring to other coronaviruses, it is known that N protein and viral genome RNA intertwine to form viral nucleocapsid, which plays an important role in the synthesis of viral RNA At the same time, N protein is relatively conservative, which accounts for the largest proportion in the structural protein of the virus In the early stage of infection, the body can produce a high level of anti-N protein antibody The N protein can be used to establish a rapid detection method of anti-2019-ncov serum antibody It can also be used to further prepare monoclonal antibodies or carry out research on the structure of the protein The team of new detection technology center of Guangdong Experimental Animal Monitoring Institute constructed pet28a-n plasmid during the Spring Festival, and successfully expressed 2019 ncov N-His recombinant protein through E.coli As a scientific and technological support unit under the Department of science and technology of Guangdong Province, Guangdong laboratory animal monitoring institute decided to provide strains to scientific research institutions and biomedical companies nationwide free of charge On the one hand, it can reduce the repetitive work of researchers, save precious time, and avoid the waste of scientific research funds caused by repeated synthesis of virus gene sequence On the other hand, it is hoped that qualified and capable units will use the protein to develop monoclonal antibodies, serological diagnostic reagents and other products as soon as possible, so as to help prevent and control epidemics Strain consultation method: contact person: Dr Congfeng Tel.: 1856510 3036 (wechat same number) 020-84106858 email: fcong@gdlami.com attachment 1: N protein sequence attachment 2: protein expression identification diagram attachment 3: strain collection form (please fill in the form below, to avoid resource waste please fill in the purpose carefully) Fill in address of strain receiving form: https://jinshuju.net/f/9bnu6j
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