Front Cell Infect Mi: Changes in intestinal mucosa can cause brain disorders

June 1, 2020 /PRNewswire/--- Mucus is the first line of defense against harmful bacteria in the gutBut can it also be part of our defense against brain disease?previous studies have shown that bacterial imbalances in the gut are linked to Alzheimer's disease, autism and other brain diseases, but the exact cause is unclearnow, a review of a study led by RMIT University suggests a key feature, namely changes in intestinal mucusSenior author Associate Professor Elisa Hill-Yardin said these changes could lead to bacterial imbalances and exacerbate symptoms of neurological disorders(photo source:"Researchers have previously shown that changes in intestinal mucus affect the balance of bacteria in the intestines, but so far no one has linked intestinal mucus to the brainOur study shows that people with autism, Parkinson's disease, Alzheimer's disease and multiple sclerosis have different types of bacteria in the gut mucus, as do the number of good and bad bacteriaThis is a new intestinal brain connection that provides scientists with a new way to explore, as we are looking for ways to better treat brain diseases with the goal of a "second brain""
scientists are learning that brain disease affects neurons in the gutNeurons in the brain and intestinal nervous system are affected by autism, according to RMIT researchersnew review suggests that reducing intestinal mucus protection may make people with neurological disorders more prone to gastrointestinal problemsSevere intestinal dysfunction can exacerbate symptoms of brain disease, which can seriously affect the quality of life of patients and their families, the authors said" our work shows that microbial engineering and regulating gut mucus to enhance good bacteria have the potential to treat neurological diseases(Bio Valley Bioon.com) Source: Changes in Gut mucus are linked to brain disorders
original origin: Herath, M., et al (2020) The Place of the GastrointestinalAl Mucus System in The Homealostasis: Implications for Frontiers in Cellular and Infection Microbiology
doi.org/10.3389/fcimb.2020.00248.