Front Med: Electroacupuncture on the microbial spectrum of patients with constipation associated with antipsychotics

Antipsychotic drug-related constipation (APRC) is one of the most common side effects of taking antipsychotic drugs.

Antipsychotic drug-related constipation (APRC) Antipsychotic drug-related constipation (APRC) APRC can cause severe complications APRC can cause severe complications Limited efficacy, limited efficacy requires safe and effective alternatives, requires safe and effective alternatives

Acupuncture is a non-pharmacological option

Acupuncture and electroacupuncture (EA) treatment of constipation electroacupuncture (EA) treatment of constipation change microbe-derived metabolites change microbe-derived metabolites can promote bowel movement can promote bowel movement

A recent study published in Frontiers in Medicine conducted a randomized, double-blind, sham electroacupuncture (SEA) controlled study to evaluate the efficacy of electroacupuncture (EA) in patients with APRC

Randomized, double-blind, sham EA (SEA) study control randomized, double-blind, sham EA (SEA) control 16S rRNA gene sequencing of 16S rRNA gene sequencing microbial spectrum assess the patient's microbial spectrum estimating patient

According to the Rome III diagnostic criteria for functional constipation, the study recruited 133 APRC patients (from Guangzhou Huiai Hospital, Zhejiang Tongde Hospital, Qinghai Third People's Hospital, Shenyang Anning Hospital)

Functional constipation Rome III diagnostic criteria of Rome III functional constipation diagnosis standard diagnostic

The duration of the EA/SEA treatment course is as follows: each treatment is 30 minutes, 3 times a week, and 12 times within 4 weeks

EA group: Take acupoints on both sides of Tianshu (ST25), abdominal junction (SP14), and Shangjuxu (ST37).

Days pivot pivot days abdominal junction abdominal junction Shangjuxu Shangjuxu on

SEA group: The acupoints were bilateral sham ST25, sham SP14, and sham ST37, respectively located 2cm from the side of the EA treatment point

According to the clinical situation, laxatives are used as emergency treatment for participants who have not had a bowel movement for 3 days or more

The main outcome indicator was changes in spontaneous bowel movements (SBMs)

The main outcome indicator is the change of spontaneous bowel movements (SBMs) The main outcome indicator is the change of spontaneous bowel movements (SBMs)

The results showed that compared with SEA treatment, EA treatment was more effective during treatment and during follow-up

EA treatment can significantly improve SBMs after treatment.

APRC safe and effective treatment of patients with EA EA APRC effective treatment of patient safety tips you can use EA treatment APRC for specific microorganisms Tip You can use EA treatment APRC for specific microorganisms

 

Literature source:

Literature source:

Zheng Yuanjia.

Zheng Yuanjia.
, Jiang Xiumin.
, Gao Yacen.
, Yuan Lexin.
, Wang Xiaotong.
, Wu Shengwei.
, Xia Yucen.
, Yao Lin.
, Yan Jinglan.
, Liu Lanying.
, Wei Yingdong.
, Song Zhiqiang.
, Yu Lin .
, Chen Yongjun (2021) Microbial Profiles of Patients With Antipsychotic-Related Constipation Treated With Electroacupuncture Front Med (Lausanne), 8 (undefined), 737713.
doi:.
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10.
3389 / fmed.
2021.
737713

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