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Alzheimer's disease (AD) and Parkinson's disease (PD) are both primary central nervous system degenerative diseases, the cause of which is not yet clear.
clinical symptoms, multiple cases are hidden and slow, memory and cognitive function are deteriorating, and irreversible.
many studies have shown that the earliest symptoms of AD and PD are olfactory disorders, which means that olfactory disorders may serve as a better warning of AD and PD than cognitive impairment, and that olfactory testing may have predicted earlier whether these terrible neurodegenerative diseases are possible.
recently, a team at the University of Otago tried to develop non-invasive wearable devices that could stop or reverse symptoms in the short term by stimulating the olfactory-nervous system.
researchers used electric field modeling to configure multi-electrode configurations, using wearable Google Glass prototypes to generate tiny electrical impulses on the skin to stimulate the olfactory nervous system.
the model has been validated with direct human brain records during brain surgery, and the results show that the prototype device effectively stimulates directional stimulation into the olfactory-neural regions of the brain, making the inner olfactory cortical layer more active.
wearing stimulators and electrostatus brain imaging teams are working with Soterix Medical to test their wearable stimulators in clinical trials.
say they hope the treatment will alleviate symptoms or inhibit the development of AD and PD.
now, a growing body of research shows that the earliest symptoms of AD and PD include impaired sense of smell, which they hope will improve the diagnostic rate of AD and PD.
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