Gastric Cancer: Clinical value and application of inflammatory and nutritional markers in survival prediction sourcing patients with new complementary chemotherapy for gastric cancer plus D2 lymph node sacs.
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Last Update: 2020-07-27
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Source: Internet
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Author: User
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!---- The clinical value of inflammation and nutritional markers for gastric cancer patients with new complementary chemotherapy (NACT) is not known, so the study aims to study the clinical value and application of inflammation and nutritional markers in the survival prediction of patients with new complementary chemotherapy and D2 lymph node sacs in gastric cancermethod researchers analyzed the inflammation, nutritional markers and changes in patients with local advanced gastric cancer in NACTthe forecast values are evaluated by Cox Proportional Risk Regression under three assumptionsplot the columns that include independent prognosis factors for survival predictionresults in the study included 225 patientsneutrophils to lymphocytes (NLR), platelet-to-lymphocyte ratio, lymphocyte-to-mononucleoblast ratio (LMR), systemic immune inflammation index and hemoglobin (Hgb) significantly decreased, while the BMI decreased significantly, with a significant increase in post-NACT (P.lt;0.05)when using only the NACT premarker, the nACT pre-NLR ((HR) s 1.176, P s 0.059) shows the trend associated with the total lifetime (OS)when only nACT post-tags can be used, Post NACT Hgb (HR s 0.982, P - 0.015) is a separate prognosis factorthe changes in Hgb (HR - 0.984, P - 0.025) and LMR afterNACT are independent prognosis factorsconclusions for local advanced gastric cancer, NACT can significantly reduce certain inflammatory markersthe changes of NLR, NACT after NACT and LMR in different clinical cases, related to age, sex, tumor location and clinical staging, have a certain value for survival predictionthe initial NLR increase, the greater the preoperative anemia and LMR change values, the worse the prognosis.
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