Gastroenterology: 6 Barrett esophageal screening model accuracy studies
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Last Update: 2020-07-10
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Source: Internet
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Author: User
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The guidelines recommend that patients with Barrett's esophageal (BE) should undergo endoscopyscreeningtopreventesophageal adenocarcinoma, and researchers have recently compared several clinical risk prediction models that are common in clinical practice1,241 BE patients aged 40 to 79, the researchers compared the risk scores of six predictive models (Gerson, Locke, Thrift, M-BERE, HUNT, and Kunzmann) and assessed the symptoms of gastroesophageal reflux disease (GERD) in patients, with endoscopy results as a reference criterion, and compared the ability of the models to distinguish BETWEEN BE patients and patients with early tumorsof the 1152 cases, 81 (7.0%) were diagnosedbeThe area under the subject operating characteristic curve (AuROC) with GERD symptoms only was 0.579All six predictive models were higher than GERD in identifying BE patients (GERD's AuROC was 0.579 and the range of other prediction tools 0.660-0.695) and the predictive risk was well correlated with observational risk (calibration)HUNT (0.796), M-BERET (0.773) and Kunzmann (0.763) had similar effects in distinguishing between patients with early-onset tumors (n-94) and non-BE patientsThe identification accuracy of the six models in early tumors was higher than the frequency and duration of GERD symptoms (AuROC, 0.667)HUNT, M-BERET, and Kunzmann models better identify patients with esophageal, distinguish BE patients from early tumors and non-BE patients, and have higher accuracy than gastroesophageal reflux symptoms as the basis for identification
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