Gastroenterology: Large-scale studies have shown that vitamin D can prevent colorectal cancer, and the effect is better in food

Although the overall incidence of colorectal cancer has been declining, the number of cases among young people is increasing

The Nurses’ Health Study (NHS) II is a prospective cohort study of nurses between 25 and 42 years old started in 1989

In the past few decades, people's intake of vitamin D-rich fish, mushrooms, eggs and milk has decreased a lot

Recently, the research team of Harvard University's Chen Zengxi School of Public Health published a research paper titled: Total Vitamin D Intake and Risks of Early-Onset Colorectal Cancer and Precursors in the top academic journal Gastroenterology in the field of gastroenterology

This work prospectively studied the relationship between the total vitamin D intake of 94,205 young women registered in the NHS II and the risk of early-onset colorectal cancer and pre-disease, and found that more vitamin D intake (mainly from Dietary sources) may help prevent young-onset colorectal cancer or precancerous colon polyps

The research team found 111 cases of young-onset colorectal cancer and 3317 cases of colorectal polyps from 94,205 women who were followed up from 1991 to 2015

The median vitamin D intake is 372IU/day

The increase in total vitamin D intake is associated with a decrease in the risk of early-onset colorectal cancer

The research team also evaluated the difference between dietary vitamin D and supplemental vitamin D intake

The higher the total vitamin D intake, the lower the risk of early onset of conventional adenomas

Interestingly, the researchers did not find a significant association between total vitamin D intake and the risk of colorectal cancer diagnosed after the age of 50

In general, higher total vitamin D intake is associated with a lower risk of younger-onset colorectal cancer and pre-disease (adenoma or polyps)

Original source:

Hanseul Kim, et al.