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Unhealthy eating patterns may increase the incidence of colorectal cancer (CRC) before the age of 50 (ie, early-onset CRC)
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Because of the metabolism of sulfur-containing microorganisms in the diet, hydrogen sulfide (H 2 S) is produced, which is a gastrointestinal carcinogen that is difficult to measure on a large scale
Unhealthy eating patterns may increase the incidence of colorectal cancer (CRC) before the age of 50 (ie, early-onset CRC)
The researchers evaluated the patients’ long-term adherence to the sulfur microbial diet, which is a dietary index based on the increase of 43 bacterial species related to sulfur metabolism.
This study is a prospective cohort study and the accepted acceptance The 59013 patients undergoing endoscopy were all at risk of CRC, and their dietary assessments were conducted every four years through a validated food frequency questionnaire and the 1998 adolescent dietary intake assessment
.
The results of the study showed that there were 2911 cases of early-onset adenoma in all patients
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After adjusting for the identified risk factors, a higher sulphur microbial diet score was associated with an increased risk of early-onset adenoma (OR Q4vs.
This study confirms that the interaction between diet and intestinal sulfur metabolizing bacteria in young women plays an important role in the development of early-onset colorectal cancer
.
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Original source:
Long H.
The sulfur microbial diet is associated with increased risk of early-onset colorectal cancer precursors.
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