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Gavo cel is designated by the FDA as an orphan drug for cholangiocarcinoma

 Last Update: 2021-09-12
 Source: Internet
 Author: User

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Gavo-cel is a new type of cell therapy consisting of autologous genetically engineered T cells expressing a single domain antibody that recognizes human mesothelin, and fused with the CD3-ε subunit, which acts on the expressive T cell receptor.

The new clinical data from Gavo-cel's dose increase in the phase 1/2 clinical trial for the treatment of refractory mesothelin-expressing solid tumors will be highlighted as part of the oral report at the ESMO meeting in 2021

(Picture from ESMO official website)

(Picture from TCR2 official website)

Mesothelin is a cell surface glycoprotein that is highly expressed in a variety of solid tumors, including malignant pleural/peritoneal mesothelioma, ovarian cancer, cholangiocarcinoma, breast cancer and pancreatic cancer

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Cholangiocarcinoma therapy Gavo-cel received FDA orphan drug designation

11-05

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Gavo cel is designated by the FDA as an orphan drug for cholangiocarcinoma

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Cholangiocarcinoma therapy Gavo-cel received FDA orphan drug designation