gcMeta Platform: Effectively Supporting The Microbiome Research in China
Last Update: 2020-06-20
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On October 26th, Nucleic AcidS Research published an online paper entitled Metgca: a Global Board of Metagenomics platform to support the standard, center and analysisof microbiome dataThe gcMeta platform is a management, analysis and release platform for microbial genome and microbiome data, providing one-stop services from data storage, data analysis to data publishing for domestic and foreign users, and has now integrated data from the Microbiome program of the Chinese Academy of Sciences and many important projects at home and abroadThe release of this platform will effectively support the research of the microbiome in China and provide important support for the implementation of the national microbiome plan in China in the futurein recent years, the United States and the European Union have launched microbiome-related research projectsHowever, the collection, storage, function mining and exploitation and utilization of microbiome big data has always been the core problem that restricts the development of microbiomeAt present, there are problems such as the ununiform standard, the lack of cross-disciplinary data integration, the high-quality reference database and the deep mining technology of data in the data management of microbiomeIn 2017, the Chinese Academy of Sciences launched the "China Microbiological Group Program" project, which aims to further strengthen the common technology and platform advantages of the Chinese Academy of Sciences in the research and development and utilization of microbiomes, focus on the "human health and environment" microbiome, develop new and new microbiome methods and new technologies; At the same time, on the basis of the standardization of microbiome data, a microbiome big data calculation, storage and sharing platform will be established, a new method of microbiome big data mining will be developed, and the system management and efficient utilization of microbiome data resources in China will be realizedgcMeta has established a one-stop system for microbial genome, metagenomics and transcription group management, online data analysis, visualization and data publishingAt present, more than 120,000 sample data from international related platforms (NCBI, EBI, MG-RAST, etc.) and major projects (HMP, Tara, etc.) have been integrated, and more than 2000 sample data from Chinese scientists have been consolidated, with a total data volume of more than 120TBThe platform provides users with a multi-level data management and permission control system that can be used by each research group to manage unpublished data and share it within the research group, or it can also be published and exposed online by internal management dataThe platform provides a unique PID number based on the Persistent Identifier (PID) system for public publication and subsequent data reference and analysis in academic journals for all public dataIn addition, the platform integrates more than 90 online data analysis tools to provide 4 sets of analytical workflows for amplification subsequences, whole genome sequences, and all analytical tools and workflows are used in a web way to facilitate users in the microbiological field to quickly master and use themUsers can easily implement a series of services such as data management, data analysis, results display and data release through the platform, the platform will also provide users with the use of support for the whole process, welcome domestic and foreign users to use the platformMicrobiological Resources and Large Data Center Shi Wenxuan and Zhai Hehui are the co-first authors of the paper, and Microbial Resources and Large Data Centerandi Ma Juncai and Wu Linxuan are co-authors of the paperThe research was supported by the Key Deployment Project of the Chinese Academy of Sciences," "Common Technology Research on Human and Environmental Health", "Research on probiotic health function sorority and the study of the metabolic mechanism of food nutrition based on intestinal microbiome", the Chinese Academy of Sciences Class A pilot special "Big Data on Earth", and the cloud project in the field of microbiology in the field of information technology of the Chinese Academy of SciencesSource: China Biotechnology Network
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