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    Home > Medical News > Medical World News > Gene modified maggots can accelerate wound healing

    Gene modified maggots can accelerate wound healing

    • Last Update: 2020-04-03
    • Source: Internet
    • Author: User
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    When the wound is hard to heal, it can be handed over to maggots Researchers at the University of North Carolina in the United States have genetically modified the larvae of the green bot fly to secrete human growth factor molecules, which has been proved to promote wound healing speed Although it may sound disgusting, it's not new to use maggots to promote wound healing In fact, it has been more than 100 years since the worm was placed on the wound Maggots can eat dead tissue, leaving only living tissue The larvae also secrete antibacterial compounds that help clean wounds It is a cheap way to treat wounds, but the effect is still in doubt Past clinical trials have not confirmed that maggots can really speed up wound healing This is where genetic engineering works The University of North Carolina team created two types of maggots: one that was genetically modified to produce human platelet-derived growth factor BB when heated to 37 degrees Celsius The second maggot is designed to release growth factors in the absence of specific antibiotics in its diet Laboratory studies have found that the first group of maggots will not die with sufficient recovery growth factors released, but the second group, which limits dietary antibiotics, will The next step is to use the modified maggots in clinical trials Although it's disgusting to put maggots on the wound, it can bring benefits to diabetic patients with long-term leg and foot ulcers "Most people with diabetes who live in low - and middle-income countries don't have access to expensive treatment options, and genetically modified maggots can provide diabetes patients with a cheap wound treatment program to avoid amputation or other harmful effects," said entomologist Max Scott The study was published in the journal BMC biotechnology.
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