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In recent years, as the concept of precision medicine has advanced, genetic testing technology has been highly regarded for its commercial or medical applications, as it has been like giving the human body a detailed instruction about where you have the talent and what diseases may be in the future.
, the New York Times recently conducted an in-depth study and report on the topic, the problem is not as simple as we think.
For now, at least, it's a luxury to expect genetic testing to give you a lifetime's talent and health.
genetic tests are also "reworked", according to the New York Times, in a recent study, genetics researchers re-evaluated data on 1.45 million patients who had been genetically tested between 2006 and 2016 to see if the results in those original reports were true.
lab has released new genetic test reports on 60,000 of them, meaning the old results have been completely replaced by new data.
many patients who carry a mutated gene that has been reclassified are still kept in the dark. "The system is still in disarray," said Dr. Sharon Plone, a clinical genetician at The Baylor College of Medicine at
.
", she said, "in fact, there is no systematic way to tell patients and doctors with certainty what the risk of a patient will be in the future."
"Because of mutations that were previously considered harmless, they may show health hazards in a few years, while others previously thought that dangerous mutations may prove benign at any time."
simply put, the New York Times report tells us that the genes you tested a few years ago may now be a complete result.
of course, such problems affect a small number of patients, most of whom have unusual genetic mutations.
more common disease-causing mutations -- such as those that predict that you may have breast or colon cancer -- have been studied in depth, so their meaning often needs to be questioned.
was widely regarded as "amazing" genetic testing, what went wrong? To figure out this problem, it is necessary to say the mechanism of genetic testing.
it is well known that the information carried by the DNA chain in the human chromosome determines our physiological structure and behavior.
about 1.5% of the code is responsible for the composition and structure of all proteins in the human body, and the rest of the code is responsible for the construction and life cycle of the human body as a complex body.
But this simple description makes it easy for us to compare DNA information in chromosomes to computer programs: both are a sequence of code consisting of a long list of encoded elements to illustrate one or more complex tasks.
however, this analogy can easily lead to the misconception that the coding on the DNA chain, like a computer program, is "a piece of coding", in which each gene point determines a different physiological or behavioral structure.
is based on this understanding that we are trying to build an interpretation of DNA information systems, namely genetic testing.
but recent studies have shown that these attempts are very challenging, with the biomechanism properties of proteins facing the lack of "singleness" (functionally unique) and "uniqueness" (unique).
a simple protein composition, may be associated with several or even dozens of gene sites, a gene point changes, will be "one shot and move the whole body."
this undoubtedly increases the difficulty of genetic testing by several orders of magnitude, the human path of genetic exploration is longer than imagined, which has resulted in some genetic testing involving complex pathology every few years to "rework" phenomenon.
Don't treat it as a "fortune teller" as mentioned above, as recent studies have shown that the complexity of DNA coding is not as complex as a computer program.
so far, the study of genetic sequencing to predict physiological lesions and even human talent stakes should still be in its infancy.
whether commercial or medical institutions, the main thing that can be done now is to track and identify the genes of a single bit.
this determines that some of the current genetic tests for red fire are based on genealogy, while others are similar to "electronic fortune tellers".
, for example, that current techniques can already be used to identify genetic errors in genetic and replication by comparing genetic methods to correspond to diseases caused by specific protein defects, so it is possible to identify the risk of certain diseases through genetic testing.
and for complex and multi-caused systemic sexual lysis, through the means of genetic sequencing to predict, but also not to achieve the desired results.
we must acknowledge that for most conditions, a stable and reliable correspondence between genes and conditions is very difficult to establish.
for example, because we have been able to track and identify some specific gene sites, so through genetic testing to achieve "recognition of ancestry", to find out a person's ancestral origin can already be done.
the current technology to be filled defects only not enough samples, can only be described more generally.
but want to determine a person's IQ, fitness, suitable for being a musician or athlete by measuring a "genius gene", in the current technical conditions seem quite arbitrary.
because of IQ, physical fitness, sense of music and other qualities are involved in a rather complex mechanism.
humans have not yet figured out how to occur at the protein level, it is even more unlikely to go deep eras to the genetic level. In addition,
, the question of what kind of influence external factors will have on gene expression is still uncertain in the academic circles.
a rather interesting but always overlooked fact: two individuals in identical twins have exactly the same chromosomes, but often develop significant differences in personality, ability, expertise, and preferences as they grow up, even in almost identical cultures.
the existence of this phenomenon is a sure reminder that simple genetic determinism is not reliable.
all in all, current research at least suggests that there is no "perfect gene" in the world, no one without the disease gene.
is not sick, when sick, what disease, how the disease is induced, what kind of talent, etc. , genetic testing alone can not be accurately determined.
scientists continue to remind the public that genetic testing has early warning value for diseases, but it cannot be over-deified, let alone treated as a "fortune-teller".
as to want to rely on genetic testing to predict their own in a certain aspect of the "genius" of what, I am afraid it is a bit whimsical.
If there is a testing agency that says it can do it - it doesn't run, it must be fooling you! Source: Qilu Evening News.