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Nearly 1,000 researchers around the world analyzed data covering more than 100 million adults and published a report on changes and drivers in the world's high-cholesterol population, according to a new study published in the British journal Nature. The report says the number of people with high blood cholesterol in low- and middle-income countries has increased since 1980, and big data surveys have found that changes in diet, behavior and medication are the driving forces behind high blood cholesterol.
blood cholesterol is a major risk factor for heart disease and stroke and has long been seen as a prominent feature of people in high-income western countries. Previous studies have looked at total cholesterol levels, but there has been no separate analysis of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol. It is believed that HDL cholesterol has the function of cleaning and unblocking arteries, while LDL cholesterol is the opposite, causing damage to arteries. Therefore, both are key markers of understanding the risk of cholesterol-related cardiovascular disease.
1,000 researchers worldwide analyzed data from 1,127 studies covering 102.6 million adults and assessed trends in cholesterol levels in the global population from 1980 to 2018. They found that total cholesterol levels and non-HDL cholesterol levels rose in low- and middle-income countries, particularly in East and South-East Asia, while in high-income Western countries, particularly in north-west, central and eastern Europe, fell.
, non-HDL cholesterol levels in the Population of Belgium and Iceland have declined most significantly since 1980. In 1980, ChineseHDL cholesterol levels in the mouth were lowest, but rose in 2018. Non-HDL cholesterol was considered one of the factors affecting 3.9 million deaths worldwide in 2017, half of which occurred in East, South-East and South Asia (only a quarter of that figure in 1990).Majid Aizati, a researcher at Imperial College London and author of the
paper, said the results should draw enough attention to the need for countries to adopt policy measures to help people replace saturated fat in their diets with unsaturated fats on a global scale and to promote improved treatment in the medical field.
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