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    Home > Biochemistry News > Biotechnology News > Gold fights cancer! 4 gold molecules expected to change cancer treatment

    Gold fights cancer! 4 gold molecules expected to change cancer treatment

    • Last Update: 2020-06-01
    • Source: Internet
    • Author: User
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    You've thought a lot..(Seriousface.jpg) Recently published a study in the European Journal of Chemistry by researchers at RMIT University in Melbourne, Australia, announced four gold-based bioactive molecules for cancer treatmentIn fact, the use of precious metals to fight cancer is no longer a rarityin the mid-1960s, researcher Barnett Rosenberg, in an experiment with Ecoli, found that energizing the platinum electrodes caused the cell division in the sample to stop suddenlyHe soon found out why: the electrodes produced a compound called cisplatinfurther researchRosenberg has revealed the significant effect of cisplatin in inhibiting tumor growth in miceIn 1978, cisplatin was finally approved as an important tool for humans to fight cancer, both alone and in combination with other compoundsOver the past few decades, platinum-based cisplatin has become the compound of choice for the treatment of many cancersIt is particularly effective in preventing testicular cancer, with a success rate of more than 90%However, cisplatin and other metal-based anti-cancer drugs are inherently toxic, they are resistant to other drugs in the human system, and lack long-term stability, so their use is limitedThese new studies have shown that these gold molecules are 24 times more effective at killing certain cancer cells than cisplatinResearcher Neda Mirzadeh said: 'Developing this new cancer treatment has incredible potential to provide lasting action and precision"
    medicinal metal compounds
    thousands of years ago, people have known that metals have a therapeutic effect The ancient Egyptians and Chinese successfully used gold and copper to treat syphilis Similarly, doctors in ancient Greece used sand (mercury sulfide) to treat eye diseases, chandanomy and other diseases metals are naturally occurring elements that involve a range of cellular activities that are compatible with the human body -- at least to some extent Gold, with good body tolerance and elongation, has the special properties of absorbing light and then releasing heat, gold special physical and chemical properties, can be used in tumor research , researchers at the University of Fort Fort Fort Lauderdale made gold-diameter gold nanoparticles, which can target tumors, release heat and destroy nearby cancer cells when exposed to light sources, and attach drugs to the surface of nanoparticles and pass them to specific locations Further studies have shown that polymer-coated spherical gold nanoparticles boost the immune system the four new designs of the gold molecule The molecular engineering team at RMIT in Melbourne, Australia, shared decades of experience developing gold molecules for specific uses and designed four new gold-based molecules that allow them to target cancer cells precisely without harming healthy cells these new molecules inhibit the production of thiopental protease, an enzyme associated with cancer growth and drug resistance In addition, these molecules also have anti-inflammatory properties, which help to relieve the swelling that often occurs at the tumor site This ability also suggests that these molecules may play a role in future arthritis treatments , researchers have completed preclinical studies in vitro and in vitro to demonstrate the cytotoxic effects of molecules they designed on prostate, breast, cervical, melanoma and colon cancer cells They also reduced the growth rate of tumors in animals by 46.9 percent, compared with 29 percent for cisplatin   Suresh Bhargava, head of the research team, points out that gold's status as a therapeutic drug has long been pending Although gold has been market tested and has been used for thousands of years to treat a variety of diseases, it has not been scientifically validated These four new molecules changed the situation "Our work not only helps provide a missing evidence base, but also provides a new family of molecules tailored to enhance the natural healing properties of gold the molecular engineering team is currently preparing to conduct human clinical studies.
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