Goliath THR-beta agonist ASC41 approved for NASH indication clinical trial

REVIEW: NASH1 class innovative drugs ASC41 clinical trial application has been approved by the Chinese State Drug Administrationsong ceremony Pharmaceutical Co., Ltdannounced yesterday that it developed in-house treatment of nonalcoholic steatohepatitis (Non-alcoholic Steatohepatitis, referred to as NASH) Class 1 clinical trials of new medicines ASC41 application is Chinese State Drug Administration approvalsong NASH gift has another two drug candidates: in ASC40 and drug candidates in Pre-IND stage Ⅱ clinical trial stageASC41 expected to be used alone or in combination with a drug or candidate ASC40 Pre-IND is used in combination therapy stage NASHASC41 is an oral thyroid hormone receptor β (THR-beta) agonists; ASC40 orally is a fatty acid synthase (Fatty Acid Synthase, referred to as of FASN) inhibitorssong ceremony Founder, Chairman and CEO DrWujin Zi said:"very excited, as the first internal R & D NASH drug candidates, clinical trial application ASC41 of the State Drug Administration approval in the field of NASH , ritual song has three drug candidates against three different targetsritual song is accelerating innovative drug development process, as soon as possible to benefit the global nonalcoholic steatohepatitis patients"
on non-alcoholic steatohepatitis
non-alcoholic steatohepatitis (NASH), also known as metabolic steatohepatitis, mainly for the accumulation of fat in the liver of unknown causes, it can lead to chronic liver inflammation and liver cell damage and can lead to fibrosis and cirrhosis, eventually lead to liver cancer or liver failure, according to "Journal of Hepatology" magazine shows that in 2016 the number of non-alcoholic fatty hepatitis China is 32.81 million, is expected in 2030, this figure will reach 48.26 millionAt present, the world is no curative drug for the treatment of non-alcoholic steatohepatitis listedEditor: Meng MengRelated Tags:National , ritual song pharmaceutical , NASH
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