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    Home > Food News > Food Articles > Goto: The core function of sleep - PK oxidative stress

    Goto: The core function of sleep - PK oxidative stress

    • Last Update: 2021-02-18
    • Source: Internet
    • Author: User
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    In 2017, Yu Zhengkangxun put forward the public welfare slogan of "Do a good job in the health industry, make a health example first", calling on the elite of the nutrition and health industry to take the lead in taking action and strive to improve nutrition, health level and disease prevention ability.Thirty-six thousand days, almost a third of our lives we sleep.in modern society, chronic sleep deprivation has become a common phenomenon, and a deep understanding of sleep is becoming increasingly important, as there is much evidence of a correlation between sleep deprivation and negative health effects., the core function of sleep remains a mystery to us.a new study published July 12 in PLOS Biology, Vanessa Hill and Mimi Shirasu-Hiza of Columbia University found that sleep-deprived fruit fly mutants have a common flaw in their sensitivity to acute oxidative stress, suggesting that sleep supports the antioxidant process."Oxidative Stress" is a physiological concept proposed by Sohal in the United States in 1990, which refers to the physiological and pathological reactions of cells and tissues caused by excessive accumulation of reactive oxygen freelance fundamentals in the body under the condition of internal and external environmental stimulation. As an eco-nutrition product platform, the newly-promoted "Net Red" KB-120 is able to develop more scientific and personalized products that balance oxidative stress on demand.to understand the two-way relationship between sleep and oxidative stress in fruit flies is important for us to further understand modern human diseases such as sleep disorders and neurodegenerative diseases.Why are we sleeping? During sleep, animals become vulnerable, unable to move, and less respond to their surroundings. They cannot court, forage or escape capture. Despite the cost of sleep behavior, almost all animals sleep, suggesting that sleep meets some of the necessary functions that are preserved during evolution, both for humans and fruit flies.that if a core health function requires sleep, animals with significantly less sleep should have some common flaw in this core function. In the study, the researchers used sleep-deprived
    (Drosophila) mutants. They found that fruit fly mutants do share a common flaw: they are all highly sensitive to acute oxidative stress.oxidative stress is caused by too many freelances, which can damage cells and cause organ dysfunction. Toxic free agents, or reactive oxygen, build up in cells through normal metabolism and environmental damage. If sleep function can protect against oxidative stress, then increasing sleep can increase resistance to oxidative stress.
    Hill and colleagues used pharmacology and genetics to verify that the theory was correct.Ultimately, the authors suggest that if sleep has antioxidant effects, oxidative stress will certainly regulate sleep itself. They found that reducing oxidative stress in the brain by overexpressing antioxidant genes also reduced sleep. This fact also confirms their hypothesis.above, these results show a two-way relationship between sleep and oxidative stress, which means that sleep function protects the body from oxidative stress, which helps induce sleep.study is linked to human health because sleep disorders are associated with many diseases associated with oxidative stress, such as Alzheimer's, Parkinson's and Huntington's disease. Lack of sleep may make individuals more sensitive to oxidative stress and subsequent diseases. Conversely, pathological damage to antioxidant reactions can also lead to sleep deprivation and related diseases.paper,
    A Bidirectional Relationship between sleep and oxidative stress in Drosophila, from Columbia University and published in PLOS Biology, was compiled by China Biotechnology Network (WechatID: biotech-china) under the original title "The Important Role of Sleep - Antioxidants!" , please indicate the reprint
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