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    Home > Active Ingredient News > Infection > Guangxi Medical University Research: Nebulized inhalation of Mycobacterium vaccae vaccine may shorten the time for new coronary pneumonia nucleic acid to turn negative

    Guangxi Medical University Research: Nebulized inhalation of Mycobacterium vaccae vaccine may shorten the time for new coronary pneumonia nucleic acid to turn negative

    • Last Update: 2021-04-19
    • Source: Internet
    • Author: User
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    Data Map Science and Technology Daily, Nanning, April 5th (Reporter Liu Hao) On the 5th, the reporter learned from Guangxi Medical University that the team of Professor Li Chaoqian of the school carried out "Aerosolized inhalation of Mycobacterium vaccae vaccine in the treatment of COVID-19 clinical research-1 A "randomized double-blind controlled experiment" study showed that the technology can shorten the time for nucleic acid to become negative, and there is no severe disease, reyang and obvious adverse reactions.

    Related research results were recently published in the international journal "Journal of Aerosol Medicine and Pulmonary Drug Delivery.
    "
    Severe Acute Respiratory Syndrome Type 2 Coronavirus is highly contagious, and there is currently no specific treatment.

    In February 2020, Professor Li Chaoqian's team began to conduct research at Nanning Fourth Hospital (a designated hospital for the treatment of new coronary pneumonia).

    In this randomized, double-blind, placebo-controlled experimental study, the research team included 31 ordinary adult cases of new coronary pneumonia who were diagnosed and admitted to the hospital from January 22, 2020 to February 17, 2020.

    According to the research team members, the selected cases were randomly divided into 2 groups: group A (conventional treatment group) and group B (mycobacterium vaccae vaccine combined with conventional treatment group).

    Group A was nebulized inhalation of 10 ml of normal saline and underwent the guideline routine treatment, group B nebulized inhalation of Mycobacterium vaccae (dissolved in 10 ml of normal saline) and underwent the guideline routine treatment.

    Both groups were atomized and inhaled with SW-Ⅱ jet nebulizer at an oxygen flow rate of 5 liters per minute until the liquid was sucked out, once a day for 10 consecutive days.

    The results showed that the time interval of viral RNA negative in group B was 2.
    9 days, which was significantly shorter than that in group A of 6.
    8 days.Professor Li Chaoqian’s team has been engaged in respiratory mucosal immunity research for many years, and has found that inhalation of inactivated mycobacteria can effectively improve the symptoms of moderate persistent asthma in adults and children, reduce the number of acute attacks and the need to use relievers, and at the same time, inhalation of inhalation Live mycobacteria can quickly increase the level of interferon in the respiratory system, correct the imbalance of helper T cell 1 and helper T cell 2, so as to effectively and safely prevent asthma.

    Li Chaoqian said that this technology is based on this, based on the similarity of respiratory virus infection-induced asthma and the immune response of the two, speculated that this method can rapidly up-regulate non-specific natural antiviral immunity such as respiratory interferon, and it has been successful in animal experiments.
    The prevention of respiratory syncytial virus infection is carried out on the basis of.

    "The team's series of basic, animal and clinical research results show that the new technology and theoretical research results are expected to provide a new approach and theoretical basis for clinical non-specific early prevention and treatment of respiratory virus infections.

    " Li Chaoqian said.

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