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At present, the emergence of direct oral anticoagulants (DOAC) has led to a shift in the management of atrial fibrillation (AF) and thromboembolism , because the drug has a rapid onset of action, a short half-life, and predictable and better pharmacokinetic effects.
Security .
However, in patients undergoing invasive surgery, the management of anticoagulation remains challenging
.
Colonoscopy and polypectomy have been shown to reduce mortality associated with colorectal cancer (CRC)
At present, the emergence of direct oral anticoagulants (DOAC) has led to a shift in the management of atrial fibrillation (AF) and thromboembolism , because the drug has a rapid onset of action, a short half-life, and predictable and better pharmacokinetic effects.
Security .
To this end, the researchers conducted a Hong Kong-wide retrospective cohort study involving Hong Kong from 2012 to 2020
.
The included patients were confirmed to receive oral anticoagulants and undergo colonoscopic polypectomy
The results of the study confirmed that compared with warfarin, apixaban was associated with a lower risk of PPB (HR (aHR) 0.
39, 95% CI 0.
Apixaban
Compared with warfarin, dabigatran, and rivaroxaban, apixaban significantly reduces the risk of PPB and thromboembolism, especially in elderly patients with right polyps
.
.
Original source:
Louis HS Lau.
Risks of post-colonoscopic polypectomy bleeding and thromboembolism with warfarin and direct oral anticoagulants: a population-based analysis.
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