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    Home > Active Ingredient News > Digestive System Information > Gut: Do you have a drink?

    Gut: Do you have a drink?

    • Last Update: 2021-05-22
    • Source: Internet
    • Author: User
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    Lead: Does it prevent cancer? It's better to start by quitting sugary drinks.

    Wingatchalian The incidence of early-onset colorectal cancer (EO-CRC) has been increasing in many high-income countries over the past 20 years.

    Before 2000, the consumption of sugar-sweetened beverages (SSB) in the continuous birth cohort in the United States increased significantly, with adolescents and young people under 50 having the highest consumption.

    At the same time, in recent years, the diagnosis of colorectal cancer has increased among people under the age of 50, and researchers are looking for reasons.

    As more and more evidence supports metabolic conditions, including obesity in adults and adolescents, as well as early-onset type 2 diabetes, a reasonable link to EO-CRC.

    Although existing epidemiological evidence suggests that the link between SSB and CRC risk is uncertain, emerging experimental studies strongly support this link.

    Artificially sweetened beverages (ASBs) and 100% fruit juices are considered to be alternatives to SSBs, and their consumption is increasing among teenagers and adults, but there are still many questions to be answered regarding their long-term health effects.

    In view of this, a new study led by Washington University School of Medicine in St.
    Louis found that there is a link between drinking sugar-sweetened beverages and an increased risk of colorectal cancer in women under 50.

    Research results show that large amounts of sugar-sweetened beverages (13 to 18 years old) during adolescence and adulthood increase the risk of colorectal cancer.

    The study was published online in the journal Gut on May 6, 2021.

    The incidence of colorectal cancer in young people is still relatively low, but in the past thirty years, the incidence of this disease has been on the rise, and we don’t know why, this is already a major public health problem, and it is also cancer prevention.
    Priority.Due to the increase in colorectal cancer at a young age, the average age of colorectal cancer diagnosis has dropped from 72 to 66 years.

    Compared with cancers in the elderly, the diagnosis of these cancers is more advanced and has different characteristics.

    The research team’s laboratory is funded by the National Cancer Institute (NCI) and the National Comprehensive Cancer Network to identify risk factors, molecular structures and precise screening strategies for these cancers so that these diseases can be detected and even prevented early.

    In the past work, it has been proved that poor eating habits are associated with an increased risk of early onset of colorectal cancer precursors, but we have not checked specific nutrients or foods before.

    The researchers analyzed data from the "Nurse Health Study II", a large-scale population study that tracked the health of nearly 116,500 female nurses from 1991 to 2015.

    Participants conducted a survey every four years and used valid food frequency questionnaires (FFQs) to report on beverage intake during adulthood.

    Among all participants, more than 41,000 participants were also asked to recall their eating habits during adolescence.

    Researchers identified 109 early-onset colorectal cancer diagnoses among nearly 116,500 participants.

    Compared with those who drank SSB <1 serving/week in adulthood, women who consumed ≥ 2 servings a day had more than doubled the risk of EO-CRC, and each additional serving/day increased the risk by 16%.

    At the age of 13-18, every additional serving of SSB intake per day increases the risk of EO-CRC by 32%.

    Substituting artificially sweetened beverages, coffee, reduced-fat milk or whole milk for SSB intake per serving/day in adulthood is associated with a 17%-36% reduction in the risk of EO-CRC.

    The intake of sugar-sweetened beverages in adulthood and the risk of early-onset colorectal cancer.
    Substitution of sugar-sweetened beverages with other beverages and the risk of early-onset colorectal cancer.
    Therefore, the study concluded that higher SSB intake in adulthood and adolescence is associated with women Related to the high risk of EO-CRC.

    Reducing SSB consumption by teenagers and young adults may be a potential strategy to reduce the growing burden of EO-CRC.

    The consumption of sugar-sweetened beverages is associated with metabolic health issues, such as type 2 diabetes and obesity, including children.

    However, little is known about whether this high-sugar beverage may increase the incidence of colorectal cancer in young people.

    Like the incidence of early-onset colorectal cancer, the consumption of such beverages has increased in the past 20 years, with teenagers and young people between 20 and 34 years old.

    The researchers said: "Despite the small number of cases, there are still strong signals that sugar intake, especially in early life, plays an important role in increasing the risk of colorectal cancer in adulthood.

    This study is with us.
    The combination of past work linking obesity and metabolic status with the high risk of early-onset colorectal cancer suggests that metabolic problems, such as insulin resistance, may play an important role in cancer development in young people.

    "Considering the increase in the ratio, The American Cancer Society recently lowered the recommended age for first screening colonoscopy from 50 to 45 for the average risk population.

    According to the guidelines, those with other risk factors (such as family history of the disease) should start earlier.

    Since the study only included female nurses, most of whom were white, more work is needed to study this connection between people with more diverse races and genders.

    Although sugar-sweetened beverages are associated with an increased risk of early-onset colorectal cancer, other beverages (including milk and coffee) are associated with a reduced risk.

    This observational study cannot prove that drinking sugar-sweetened beverages can cause this type of cancer, nor can it prove that drinking milk or coffee has a protective effect, but the researchers said that replacing sugar-sweetened beverages with sugar-free beverages (such as milk and coffee).
    It is a better choice for long-term use and long-term health.

    In view of these data, the researchers recommend that people avoid sugary beverages and choose beverages such as milk and coffee that do not contain sweeteners.

    Reducing the intake of SSB and/or replacing SSB with other healthier beverages among teenagers and young adults may be a potentially actionable strategy to alleviate the growing burden of EO-CRC.

    Original Source: Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset colorectal cancer among women .
    doi: 10.
    1136/gutjnl-2020-323450
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