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Colorectal cancer (CRC) is the leading cause of cancer-related deaths worldwide
.
Obesity is a recognized risk factor for colorectal cancer.
Colorectal cancer
Recently, a research article was published in Gut, an authoritative journal in the field of digestive diseases.
Researchers aimed to assess the relationship between maternal obesity, pregnancy weight gain, birth weight and adult children's CRC
.
The Child Health and Development Study was a prospective cohort of women who received prenatal care in Oakland, California between 1959 and 1966 (N=18751 live births, 14507 mothers)
.
Clinical information is extracted from the mother’s medical records from the first 6 months of pregnancy to delivery
Child diagnosis
In the annual follow-up of 738,048 person-times, 68 children were diagnosed with CRC, and half of them (48.
5%) were younger than 50 years old at the time of diagnosis
The results of this study indicate that intrauterine events are an important risk factor for CRC and may increase the incidence of CRC in young adults
Original source:
Caitlin C Murphy.
et al.
Maternal obesity, pregnancy weight gain, and birth weight and risk of colorectal cancer .
Gut.
2021.
https://gut.
Maternal obesity, pregnancy weight gain, and birth weight and risk of colorectal cancer in this message