GUT: Not to be underestimated!

Gastric cancer (GC) is the fifth most common cancer in the world and the third leading cause of cancer-related deaths.

Gastric cancer (GC) is the fifth most common cancer in the world and the third leading cause of cancer-related deaths.

Screening diameter screening reduces the mortality and morbidity of GC across the country (0.

In countries with a moderate or low incidence of GC, the method of universal endoscopic screening is not cost-effective.

For such areas, targeted endoscopic screening of high-risk groups may be a better approach.

Multiple studies have shown that the gastritis assessment (OLGA) associated with gastric cancer can reliably identify subgroups of patients at high risk of GC.

Multiple studies have shown that the gastritis assessment (OLGA) associated with gastric cancer can reliably identify subgroups of patients at high risk of GC.

(A) Age-adjusted incidence of EGN, stratified by OLGIM stage.

(A) Age-adjusted incidence of EGN, stratified by OLGIM stage.

Diagnosis of IM is an important risk factor for EGN, which can increase the risk of EGN by 4.

Among them, the participants of OLGIMIII-IV stage had the greatest risk, which increased almost 20 times (HR=20.

At the same time, researchers found that if Helicobacter pylori is negative, serum trefoil factor 3 (TFF3) can distinguish OLGIM III-IV patients.

If Helicobacter pylori is negative, serum trefoil factor 3 (TFF3) can distinguish OLGIM III-IV patients.

Endoscopic monitoring for high-risk patients (OLGIM III-IV) within 2 years, and endoscopic monitoring for moderate-risk patients (OLGIM II) within 5 years to better predict the occurrence of gastric cancer.

references:

Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP).

Severity of gastric intestinal metaplasia predicts the risk of gastric cancer: a prospective multicentre cohort study (GCEP).
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