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Gynecol Oncol: The therapeutic effect of Nelatinib in patients with HER2 mutation and metastatic cervical cancer

 Last Update: 2021-04-22
 Source: Internet
 Author: User

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About 5% of cervical cancer patients have somatic HER2 mutations, which are related to poor prognosis.

The study enrolled 16 patients with HER2-mutated, persistent, metastatic/recurrent cervical cancer who had advanced or advanced disease after platinum treatment and received oral neratinib 240 mg/day and loperi in the first cycle.

prevention

The results showed that 10 (62.

In summary, the results of this study indicate that neratinib as a single agent can be used to treat patients with HER2 mutant cervical cancer without new safety incidents.

Original source:

Ana Oaknin,et al.

ncbi.
nlm.
nih.
gov/32723675/" target="_blank" rel="noopener">Neratinib in patients with HER2-mutant, metastatic cervical cancer: Findings from the phase 2 SUMMIT basket trial in this message

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