-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
In a fast-paced life, having plenty of exercise time may be difficult for many people.
, even a short exercise is good for your health.
A new study by the team at Harvard Medical School's Massachusetts General Hospital (MGH) adds evidence that 12 minutes of high-intensity cardiopulmonary exercise can affect blood levels of nearly 85 percent of metabolites, involving a variety of mechanisms that promote cardiovascular metabolic health.
the study was published recently at the American Heart Association's (AHA) 2020 Scientific Conference and the AHA journal Circulation.
screenshot source: The Circulation study, conducted in the Framingham Heart Study, compared blood levels of 588 metabolites before and after 12 minutes of vigorous exercise (an average of 11.9±2.1 minutes) among 411 middle-aged people (average age 53±8 years, 63% of women±
resting state, the researchers detected changes in 502 (85 percent) metabolites, most of which are good for heart metabolic health, after exercise.
, for example, insulin resistance-related metabolites decreased, glutamate levels decreased by 29% and DMGV (dmethyl pentaginate) decreased by 18%.
promote lipid degradation, promote the transformation of white fat (mainly stored fat) into brown fat (burning energy-based), and improve oxidative stress and other metabolites increased.
these key findings were also repeated in a separate sample population.
Of the 783 other subjects in the Fleingham Heart Study (average age 54±8 years old and 51% female), the researchers repeatedly tested 177 metabolites, and after brief and intense exercise, 164 (92.6%) metabolites showed consistent and beneficial changes.
interesting is that different metabolites have different physiological responses to exercise, such as low DMGV levels, which may mean better cardiopulmonary adaptability.
, different metabolites may provide a unique indicator of a person's physical health, just as blood tests currently reflect kidney and liver function through different indicators.
Nayor, lead author of the paper, said Dr. Matthew Nayor, a cardiologist at Massachusetts General Hospital. The
team identified four metabolic characteristics that responded differently to exercise and again analyzed whether these metabolic changes reflected actual health outcomes in a separate group of 2,045 subjects (average age 55±10 years old and 51 percent of women), and found that two metabolic characteristics were closely related to the risk of death.
addition, the team found that the degree of change in metabolites was not only related to exercise volume and peak movement, but also to gender and body mass index (BMI), and that obesity may give people some resistance to the benefits of exercise.
" has accumulated a great deal of knowledge about the effects of exercise on the body's heart, blood vessels and inflammatory systems, but our study fully reflects the metabolic effects of exercise by linking specific metabolic pathways to exercise indicators and long-term health outcomes.
, lead author of the study and head of heart failure at Massachusetts General Hospital, said.
References, Matthew Nayor, et al., (2020). Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community. Circulation, DOI: Bursts of exercise can lead to significant improvements in indicators of metabolic health. Retrieved November 17, 2020, from