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Written | Edited by Wang Cong | Nagashi Typesetting | Water Written According to statistics from the World Health Organization (WHO), colorectal cancer is the world's third most common cancer type and second most fatal cancer type.
Colorectal cancer can occur at any age, but most of it only affects the elderly over 50 years old.
The incidence of colorectal cancer in the young population is very low.
However, in the past 30 years, the incidence of colorectal cancer among young people under the age of 50 has been increasing.
Due to the increase in the incidence of colorectal cancer in young people, the average diagnosis age of colorectal cancer has been advanced from 72 to 66.
Researchers are still exploring the reasons behind the rejuvenation of colorectal cancer.
On May 6, 2021, researchers from Harvard University School of Public Health, Washington University School of Medicine and other units published in the top journal Gut in the field of gastroenterology, entitled: Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset A research paper on colorectal cancer among women.
The study showed that women who consume a lot of sugar-sweetened beverages during adolescence (13 to 18 years) and adulthood increase their risk of colorectal cancer before the age of 50.
This also reminds us that we should reduce our sugar intake.
The corresponding author of the study is Cao Ying of the University of Washington School of Medicine, and the first author is Jinhee Hur of the Harvard School of Public Health.
Many studies have confirmed that the consumption of sugar-sweetened beverages is related to metabolic health problems, such as type 2 diabetes and obesity.
In the past few decades, the consumption of sugar-sweetened beverages has been increasing rapidly, among which children, adolescents, and young people aged 20 to 34 have the highest consumption.
At the same time, the incidence of early-onset colorectal cancer has been increasing.
Is there a relationship between the two? Does the heavy consumption of sugary drinks increase the incidence of colorectal cancer among young people? Prior to this, Cao Ying's team has confirmed that poor diet quality is associated with an increased risk of early-onset colorectal cancer, but has not further analyzed specific dietary components.
The research team analyzed data from Harvard University's "Nurse Health Research II", which tracked the health of nearly 116,500 female nurses from 1991 to 2015.
Participants responded to a survey every four years.
The survey involved dietary issues, including the type and estimated amount of beverages they drank.
Among the total participants, more than 41,000 participants recalled their eating habits during adolescence.
Researchers identified 109 cases of early-onset colorectal cancer among nearly 116,500 participants.
Further analysis found that compared with women who drank less than 1 cup (240 ml) of sugar-sweetened beverages a week, women who drank 2 or more sugar-sweetened beverages a day more than doubled their risk of developing colorectal cancer before the age of 50.
.
Drinking 1 cup a day increases the risk by 16%.
In addition, between the ages of 13-18, which is a key stage of physical development and growth, drinking 1 cup of sugar-sweetened beverages a day increases the risk of colorectal cancer by 32% before the age of 50.
Cao Yin, the leader of the study, said that although the number of early-onset colorectal cancer cases is very small, there are still strong signals that sugar intake, especially at young age, may increase the risk of colorectal cancer in adulthood.
Plays an important role.
This study also echoes previous studies linking obesity and metabolic status to the high risk of early-onset colorectal cancer, indicating that metabolic problems, such as insulin resistance, may play an important role in the development of cancer in young people.
Taking into account the increase in the proportion of young people suffering from colorectal cancer, the American Cancer Society has recently reduced the recommended age for first colonoscopy from the previous 50 to 45.
Those with a family history of colorectal cancer should start screening earlier.
This observational study found that large amounts of sugar-sweetened beverages were associated with an increased risk of early-onset colorectal cancer.
It was also found that drinking milk and coffee was associated with a reduced risk of colorectal cancer.
This observational study cannot prove that drinking sugar-sweetened beverages can cause colorectal cancer, nor can it prove that drinking milk or coffee has a protective effect.
However, the research team said that in view of the results of this study, it is recommended that people avoid drinking sugary drinks and replace sugary drinks with unsweetened drinks such as milk and coffee, which is a good choice for maintaining long-term health.
Link to the paper: https://gut.
bmj.
com/content/early/2021/03/30/gutjnl-2020-323450 Open for reprint
Colorectal cancer can occur at any age, but most of it only affects the elderly over 50 years old.
The incidence of colorectal cancer in the young population is very low.
However, in the past 30 years, the incidence of colorectal cancer among young people under the age of 50 has been increasing.
Due to the increase in the incidence of colorectal cancer in young people, the average diagnosis age of colorectal cancer has been advanced from 72 to 66.
Researchers are still exploring the reasons behind the rejuvenation of colorectal cancer.
On May 6, 2021, researchers from Harvard University School of Public Health, Washington University School of Medicine and other units published in the top journal Gut in the field of gastroenterology, entitled: Sugar-sweetened beverage intake in adulthood and adolescence and risk of early-onset A research paper on colorectal cancer among women.
The study showed that women who consume a lot of sugar-sweetened beverages during adolescence (13 to 18 years) and adulthood increase their risk of colorectal cancer before the age of 50.
This also reminds us that we should reduce our sugar intake.
The corresponding author of the study is Cao Ying of the University of Washington School of Medicine, and the first author is Jinhee Hur of the Harvard School of Public Health.
Many studies have confirmed that the consumption of sugar-sweetened beverages is related to metabolic health problems, such as type 2 diabetes and obesity.
In the past few decades, the consumption of sugar-sweetened beverages has been increasing rapidly, among which children, adolescents, and young people aged 20 to 34 have the highest consumption.
At the same time, the incidence of early-onset colorectal cancer has been increasing.
Is there a relationship between the two? Does the heavy consumption of sugary drinks increase the incidence of colorectal cancer among young people? Prior to this, Cao Ying's team has confirmed that poor diet quality is associated with an increased risk of early-onset colorectal cancer, but has not further analyzed specific dietary components.
The research team analyzed data from Harvard University's "Nurse Health Research II", which tracked the health of nearly 116,500 female nurses from 1991 to 2015.
Participants responded to a survey every four years.
The survey involved dietary issues, including the type and estimated amount of beverages they drank.
Among the total participants, more than 41,000 participants recalled their eating habits during adolescence.
Researchers identified 109 cases of early-onset colorectal cancer among nearly 116,500 participants.
Further analysis found that compared with women who drank less than 1 cup (240 ml) of sugar-sweetened beverages a week, women who drank 2 or more sugar-sweetened beverages a day more than doubled their risk of developing colorectal cancer before the age of 50.
.
Drinking 1 cup a day increases the risk by 16%.
In addition, between the ages of 13-18, which is a key stage of physical development and growth, drinking 1 cup of sugar-sweetened beverages a day increases the risk of colorectal cancer by 32% before the age of 50.
Cao Yin, the leader of the study, said that although the number of early-onset colorectal cancer cases is very small, there are still strong signals that sugar intake, especially at young age, may increase the risk of colorectal cancer in adulthood.
Plays an important role.
This study also echoes previous studies linking obesity and metabolic status to the high risk of early-onset colorectal cancer, indicating that metabolic problems, such as insulin resistance, may play an important role in the development of cancer in young people.
Taking into account the increase in the proportion of young people suffering from colorectal cancer, the American Cancer Society has recently reduced the recommended age for first colonoscopy from the previous 50 to 45.
Those with a family history of colorectal cancer should start screening earlier.
This observational study found that large amounts of sugar-sweetened beverages were associated with an increased risk of early-onset colorectal cancer.
It was also found that drinking milk and coffee was associated with a reduced risk of colorectal cancer.
This observational study cannot prove that drinking sugar-sweetened beverages can cause colorectal cancer, nor can it prove that drinking milk or coffee has a protective effect.
However, the research team said that in view of the results of this study, it is recommended that people avoid drinking sugary drinks and replace sugary drinks with unsweetened drinks such as milk and coffee, which is a good choice for maintaining long-term health.
Link to the paper: https://gut.
bmj.
com/content/early/2021/03/30/gutjnl-2020-323450 Open for reprint
