echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Digestive System Information > Heart: The relationship between non-vitamin K antagonist oral anticoagulants, proton pump inhibitors and gastrointestinal bleeding

    Heart: The relationship between non-vitamin K antagonist oral anticoagulants, proton pump inhibitors and gastrointestinal bleeding

    • Last Update: 2021-08-13
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    Recently, a research article was published in Heart, an authoritative journal in the field of cardiology.


    Digestion

    The researchers conducted a cohort study using a general protocol and a general data model method.


    The study included 164,290 AF patients receiving NOAC treatment, and 272,570 annual follow-ups were conducted.


    The incidence ratio of UGIB in each subgroup

    The subjects are divided into ages 75-84 years (the number of people who need treatment for 1 year (NNTY) is 787), the age is ≥85 years (NNTY is 667), and the HAS-BLED score is ≥3 (NNTY is 378) or Concomitant antiplatelet therapy (373 people with NNTY) has the greatest protective effect in high-risk patients


    It can be seen that the simultaneous use of PPI in AF patients receiving NOAC treatment is associated with a reduction in the risk of severe UGIB


    Concurrent use of PPI in AF patients treated with NOAC is associated with a reduced risk of severe UGIB


    Original source:

    Joris Komen.


    Non-vitamin K antagonist oral anticoagulants, proton pump inhibitors and gastrointestinal bleeds

    in this message
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.