Heavy: Read through the brain health functional ingredients - the addition of fragrant leaf-based fennel

According to global dementia epidemiology statistics,
the number of people with dementia worldwide reached
44 million
in
2013 and is expected to reach

76 million
million in





2030

62%
people living with dementia live in low- and middle-income countries and will rise
to
71%
2050
. The data showed
nearly three
4 percent of people with dementia did not receive a diagnosis.Our situation is also very not optimistic, China's Alzheimer's disease patients more than
6 million
people, an average annual increase of
30
million, brain health and physical and mental health has increasingly become an important and continuously expanding health care products market.current market Ginkgo biloba, taurine,
PS
,
DHA/EPA
and other types of health food is very popular, look forward to our health food enterprises to develop more new products.collected some information about brain health ingredients here to share with you.New raw materials for anti-mental fatigue
-

Geranylgeraniol
"Mental fatigue" has become a lingering problem in modern life, mental fatigue can also bring gastritis, allergic bowel syndrome, insomnia, depression and other diseases. New ingredients to relieve mental stress and help sleep to fight mental fatigue are on the scene.
Geranylgeraniol
, sold by Mitsubishi Chemical Foods, checks that
GGOH
) is an extract from the seeds of the sebum tree from tropical America and is a new ingredient against mental fatigue. The raw material is a natural source of fennel-based fennel, showing an oily substance between pale yellow and pale yellow-green. It has the effect of increasing stomach mucus and protecting the stomach, and it also has the effect of protecting cells from stress because of its induction and anti-inflammatory effect on thermoske protein.The manufacturer's proposal for mental fatigue, as well as due to age, alcohol consumption and other improved raw materials caused by low stomach function to develop commodities, is a differentiated anti-mental fatigue new raw materials, recently attracted the attention of many brands. With lactic acid bacteria, etc. can mainly hit the gastrointestinal health, with turmeric, etc. can mainly hit the liver health and other markets.functional test, mice (
4
weeks old) were divided into
3
groups ((1) non-mental fatigue group, (2) mental fatigue group, (3) mental fatigue

Put in the fennel-based fennel group) and force the intake of
50%
content of fennel-based fennel (
600mg/kg
) or water
14
days to put mental pressure on the mice.the results, the amount of gastric mucus decreased significantly in the (2) group that applied mental pressure, and the decrease in the amount of gastric mucus decreased significantly in the (3) group of fennel-based fennel.In addition, it was confirmed that the stomach of the mice that applied the stress had received injuries, while the stomach injuries of the mice that had been given fennel were also suppressed.mitsubishi Chemical Foods is also accumulating data from clinical trials with a view to achieving a breakthrough in functional labeled foods in the field of stomach health.MCT
(mid-chain fatty acids)brain's usual source of energy is glucose. However, as aging progresses or specific diseases, glucose cannot be fully utilized. Low-energy brain cells have new things that are hard to remember, things that are remembered are not remembered smoothly, and problems such as low memory., the second energy source that can replace glucose, the ketone body, is very impressive! Ketones are derived from the body's accumulation of fat and food fat, of which "medium chain fatty acids" are the most efficient.with aging, Alzheimer's disease is on the rise. Take Japan, for example,

2012, more than
4.6 million people aged
65,
and
older in Japan, with mild cognitive impairment (
MCI)
) aboutmillion people, the combined number of people reached
65,
years of age and older
4,
people have
1
people have cognitive problems. difference between "forgetfulness" and "cognitive" symptoms, take eating as an example, as "can't remember what to eat (forgetfulness) " and "forget that you've eaten (cognitive disorders). " But the early symptoms of cognitive disorders are similar to amnesia. the largest number of cognitive disorders is Alzheimer's disease. Features are the accumulation of abnormal proteins in the brain
(
such as plaques in the elderly)
or
brain atrophy. There is evidence that the brain, which suffers from Alzheimer's disease, may be under-energised. , the energy source of the human brain is glucose. But recent studies have shown that the brain of people with Alzheimer's disease is unable to take full advantage of glucose. examined
with Alzheimer's disease through
PET CT
and found that glucose absorption was significantly reduced compared to the normal brain! Unable to use glucose brain wine can get into a state of energy deficiency, causing brain cells to hibernate and become insperienced. previously thought that "the only source of energy available to the human brain
glucose
glucose". But many studies have shown that when glucose is low in the body, the brain can use the "ketones" produced by the liver. the proportion of energy sources used in the brain showed that glucose accounted for
100%
, ketones accounted for about
60% or more during
hunger strike! Ketones are an energy source for the brain that can replace glucose. , research into the effectiveness of ketones is also progressing in curbing the progression of aging and the low brain function caused by specific diseases. ketones used in the body are acetylacetic acid, β
-
hydroxybutyric acid and acetone, and the liver makes fatty acids into ketones. Ketones are not only a source of energy for the brain, but also for muscles, hearts, etc., and tissues other than the liver. The liver lacks an enzyme system that uses ketones. in the long history of mankind, there are very few food-rich environments like modern ones, and humans have long been in an environment where it is difficult to obtain food. As a result, when the body is hungry, it uses the body's continued fat, which is further synthesized by the liver into ketones as a source of energy for each cell. glucose as a priority for your body's energy sources. Therefore, it is often difficult to synthesize ketones when glucose is abundant in the body. , even if there is plenty of glucose in the body, there are substances that can be effectively synthesized into ketones. This is the "mid-chain fatty acid" that is transported directly to the liver after ingestion
! to detect changes in the amount of ketones in the blood, intake of the same amount of medium-chain fatty acids, compared to the common fat contained in the long chain fatty acids, will be synthesized more than
10
times the ketone body. patients to apply for medium-chain fatty acids, they need to consult a doctor in advance. People with high blood sugar status, especially those
type 1 diabetes, may
"diabetic ketoacidosis" if their blood is elevated. However, when normal people ingest mid-chain fatty acids, the body's ketone body values do not rise to the level of poisoning so high. U.S. has studied the effects of medium-chain fatty acids on short-term memory. In Alzheimer's patients and people with mild certified disorders who participated in the study, the amount of ketones in the blood increased in people with medium-chain fatty acids, which inhibited memory loss. based on this result, brain cells that do not have enough glucose energy to fall into hibernation may be able to use the ketones synthesized by mid-chain fatty acids as a source of energy to revive and regenerate function. Further research is under way on the amount and intake of mid-chain fatty acids necessary to maintain brain function. . In edible oils containing medium-chain fatty acids sold on the general market, the content of medium-chain fatty acids is about
11%
, and the amount of medium-chain fatty acids ingested from healthy fats is different from that of medium-chain fatty acids in the above-mentioned study. is a that breeds in the Arctic Circle in western Alaska and flies to Australia and New Zealand in winter. The distance between Alaska and New Zealand is 11,000 kilometers, requiring an amazing amount of stamina to fly continuously without landing in the vast Pacific Ocean. study showed that the amino acid binds to midedes contained in the chest were
3 to 4
times higher than among cattle and pigs. Tuna swims at a top speed
100km/h
, and the muscles in its tail also contain large amounts of mide-glyphosate. role of methyl peptides in brain health should not be ignored. , the cause of dementia is not entirely clear, and in a sense everyone is at risk of developing dementia and needs to be prevented early. on the prevention of dementia, in addition to developing "non-disease-prone" habits in diet and exercise, it is also recommended to conduct intensive brain function training. Healthy foods with brain health ingredients are also important options, and the market for brain health products is expanding. published in 2014 and
, "The composition of mide-titides may have the effect of inhibiting memory-related brain atrophy and improving neuropsycological function", and was selected by Japan's Ministry of Agriculture, Forage and Aquaculture as the "
2014
Agricultural, Forage and Aquatic Research
10
Results". published a
human trials for older volunteers in 2015 and 2015. The trial was divided into a trial group of mide dispeptides from muscle sources and a control group taking a placebo, with cognitive tests, blood tests, and
MRI
tests after
3
months of consumption. The experimental results showed that the language ability of the elderly group who ingested metazine was significantly improved, and the effects of helping blood flow to the brain were also confirmed. based on the results, the composition of midedyl peptides may prevent the oxidation of muscle cells that cause cerebrovascular contraction, thus ensuring the elasticity of blood vessels. Because the memory function of the brain has improved significantly, the intake of mide dipeptide may play a preventive and deceleration role in the early stages of Alzheimer's disease. research on mide dignides is still in-depth, Mide dignides for dementia, there is still a lot of research space. Yellow Mushroom Extract Japanese manufacturers in
2016
listed jaundic mushroom extract (containing wheat horn sulfur
1%
or more), as a brain health raw materials are well-known, it is expected that the relevant products will soon be on the market. active ingredient, ergothione, is an antioxidant rich in mushrooms and other mushrooms and is known to have the effect of repairing genetics. The raw material
conducted a joint study with
University in 2016 to confirm that ergothione has the ability to improve learning and memory. the study, mice were
3
times a week to ingest ergo sulfide at a rate of
1kg
weight
100mg
, and to experiment with novelty after
2
weeks of intake to compare changes in learning ability. test results, the exploration time of novel things, the wheat horn sulfur ingestion group has significantly increased, proving to have the effect of improving memory and learning ability. the action function speculated that the mice ingested the ergo sulphur and digested and absorbed, the haima tooth-like return to the brain, promoting the rebirth of nerve cells, the results improved the learning ability of the mice. results have been published in the


8
, 2016 ,
63
This Japan Society of Food Science and Technology" and
2016

9 September
, "the
11th
Institute of Genetic Nutrition Academic Opportunities." the raw material company is also in-depth research on brain health of jaundic mushroom extract.
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