Hebei confirmed nearly 100 cases in 5 days, four questions about the "hidden virus"

From 0:00 to 24:00 on the 6th, Shijiazhuang City reported 50 new confirmed cases, 67 cases of asymptomatic infection, and Yantai City reported 1 confirmed case and 2 cases of asymptomatic infection.
five days, the number of confirmed cases in Hebei has risen to 90, with more than 155 asymptomatic infections.
January 7, police officers patrol the waiting hall of Shijiazhuang Railway Station in Hebei Province.
understood that from January 6 onwards, Shijiazhuang Railway Station to implement temporary strict control measures, all passengers are suspended from entering the station.
News Agency reporter Yu Yujia in a short period of time a large increase in cases and the city-wide screening of positive samples, meaning that the virus has been "hidden" in the population.
, deputy director of china's Centers for Disease Control and Prevention, said in an interview on the 5th that the number of patients is still increasing, indicating that the virus has been secretly spreading for some time.
not just Hebei, but the "hiddenness" of the virus has emerged in many places.
, Liaoning Province, had cases after 11 tests to show positive, Beijing Shunyi outbreak also showed "not easy to find" characteristics.
the new coronary pneumonia outbreak this winter, the "hidden virus" has once again become a topic of concern.
virus become more secretive? Recently, the United Kingdom, South Africa, a number of mutated virus, Hebei Province in a short period of time the rapid spread of the virus has also caused some concern.
According to the 6th night of the new crown pneumonia outbreak prevention and control press conference held in Yantai City revealed that the new crown virus found in the Palace of Yantai and Shijiazhuang found the new coronavirus is highly consoic, the virus transmission and the European import virus is highly consoopic.
However, according to genetic sequencing results released by the Chinese Center for Disease Control and Prevention on the 6th, when sequencing samples of two new cases of coronary pneumonia in Shijiazhuang and Yantai on January 2, it was found that the strain was different from the strain found in recent outbreaks elsewhere in the country, nor was it a mutated virus found in the United Kingdom and South Africa, but had 10 identical nucleotide variation points in the Russian genome sequence uploaded in July.
experts believe that the so-called secret transmission does not mean that the virus itself has changed.
Sun Tieying, director of the Department of Internal Affairs at Beijing Hospital, told Xinhua that there may be a large number of asymptomatic infected people in the affected areas, early because it is more difficult to be screened out, easy to cause the spread of the virus, so it could not be detected early, forming a secret transmission.
, but it's a wake-up call that experts say the virus's mutation is the norm and could make it more secretive.
" from the perspective of virus survival, respiratory viruses, especially coronavirus mutations may appear at any time, is the natural process of virus evolution, also has the characteristics of survival of the fittest.
some mutations may increase propagation, and some may increase toxicity.
," said Cao Qi, deputy director of infection internal affairs at Beijing Concord Hospital.
Cao Yu believes that the mutated virus will gradually be selected in the process of transmission, but the eventual emergence of what kind of mutant epidemic strain is sexual, in addition to the characteristics of the virus itself, and a region's prevention and control measures and strength also have a great relationship.
Sun Tieying also specifically warned that the virus mutation will have a greater impact on the role of the vaccine.
the countryside or a secret place of transmission? According to the flow information, the confirmed cases in Shijiazhuang Lucheng District are concentrated in xiaoguozhuang village, LiuJiazo village, Nanqiaozhai village and many other villages, many confirmed cases have participated in weddings, funerals and other activities.
According to Shijiazhuang City's first confirmed case, she only left the village twice, one was to attend a wedding, the other was to go to a relative's house near the village, the rest of the time in the village of Xiaoguozhuang activities, she also denied the network of "airport garbage pick-up infected" matter.
the source of the outbreak has not yet been determined, but the weakness of rural epidemic prevention is an indisputable fact. More than
confirmed cases involved in wedding receptions said there were not many people wearing masks in local villages, and even "a lot of people have long since not worn masks", even some of the waiters on the menu did not wear masks.
it is also worth noting that several cases took their own medicine or infusions in the village infirmary before diagnosis and failed to test for nucleic acid in the first place.
a variety of factors, leading to the original low mobility of rural areas to become the worst affected areas of the spread of the epidemic.
, believes that the outbreak in the rural areas of Lucheng is likely to be the villagers without knowing the contact with the carriers of the virus.
"With the increase of rural migrant workers, the links between urban and rural areas have increased, the boundaries have gradually blurred, and rural areas are prone to clustering, in the event of cases, it is likely to show exponential transmission."
therefore, she believes it is necessary to strengthen the promotion of epidemic prevention knowledge, improve the training of grass-roots health departments in epidemic prevention, and implement the "Four Early Principles" as soon as possible.
Wang Daming, a researcher at the Suzhou Institute of Biomedical Engineering and Technology of the Chinese Academy of Sciences, said that in addition to epidemic prevention propaganda, rural areas need to take a series of interventions, such as special circumstances more than a certain number of people need to be approved, set up administrative village prevention and control commissioners, science and technology commissioners, etc., for the key areas of prevention and control can consider sampling, centralized testing or mobile detection vehicles on-site detection of nucleic acid detection methods.
"Hidden Corners" at winter low temperatures? At present, China is experiencing cold tides in many places, and the temperature has reached a new low after winter.
low temperatures in winter increase the spread of the virus? How many "hidden corners" in cold environments can become a warmbed for virus transmission? "The particularly cold weather is at least not good news for the new coronavirus.
" Cao said that previous studies have found that the new coronavirus "is not particularly afraid of cold", can be in the cold chain of things such as long-term survival, winter low temperatures may indeed affect the virus latent and spread.
Wang Guangfa, director of the Respiratory and Critical Care Medicine Department at Peking University's First Hospital, has previously said that the current situation is still facing very severe anti-input pressure, and winter leads to longer survival after the virus leaves the body, increasing the chances of contracting human infection.
not only that, in the winter "big cold chain" general low temperature environment, in addition to continuing to prevent and control "human-to-human", the possible "human-to-human" should also be given sufficient attention.
after the cold chain logistics frequently detected nucleic acid positive, China has recently reported in some auto parts packaging specimens also detected nucleic acid positive.
said that winter is particularly conducive to the spread of the virus, there is a real possibility of secret transmission, so it is more necessary to strengthen prevention and control measures.
he believes this year's outbreak is more manageable than the same period last year.
" rural and urban areas have a certain sense of prevention and control, all aspects of epidemic prevention materials, testing reagents are more adequate.
" Sun Tieying believes that, in any case, do a good job of personal protection or the first, for respiratory diseases should still pay attention to wear masks, the residents of the epidemic areas should also be vigilant about couriers, takeaways and so on.
detection capabilities be able to deal with "hidden viruses"? Recently, a confirmed case in Dalian after 11 tests to show positive results, some areas have also appeared six rounds of testing before testing positive, the new crown virus "sly" again highlighted.
Shijiazhuang, Yantai, Hebei Province, has carried out large-scale full nucleic acid testing, emergency mobilization of a number of medical staff support.
the rapid development of the epidemic in Hebei, do you need to re-evaluate the current use of reagent detection capabilities? "Most of the reagent 'false negative' problems that have occurred before are not all reagent accuracy problems, sampling timing and methods will have a certain impact.
" Cao Yu pointed out that the current study confirmed that the most active time for the new coronavirus in the pharynx replication and excretation of the body is before and after the emergence of clinical symptoms, at this time the pharynx nucleic acid test positive is the most likely.
", but this time period is not so wide.
" Wang Daming believes that the quality of nucleic acid testing in China has been continuously improved, the national drug testing department has made a lot of efforts to prove that the overall testing capacity is effective.
Sun Tieying also said that no country can do nucleic acid detection 100 percent accurate, can do nucleic acid census has been difficult, the source of the epidemic to carry out multiple rounds of testing is the best way.
In view of the possible impact of reagent accuracy and sampling methods on test results, China has proposed in the process of updating the treatment plan for neocleopnetic pneumonia, using nucleic acid test results and clinical diagnosis results such as serum antibody testing, lung imaging, etc., to comprehensively judge case diagnosis and discharge from hospital.
Cao believes that antibody testing can be an effective complement to clinical diagnosis, but after such a long period of practice, in the face of large-scale population screening, nucleic acid testing is still the first feasible way to consider.
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