-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
In recent years, in order to increase the rate of early diagnosis and treatment of Helicobacter pylori, China has successively launched Helicobacter pylori screening projects and mobilized family members to actively carry out Helicobacter pylori screening
In recent years, in order to increase the rate of early diagnosis and treatment of Helicobacter pylori, China has successively launched Helicobacter pylori screening projects and mobilized family members to actively carry out Helicobacter pylori screening
Helicobacter pylori ( H.
What is Helicobacter pylori? What is Helicobacter pylori?
Helicobacter pylori has a high incidence in developing countries.
Helicobacter pylori has a high incidence in developing countries.
1 ) The main symptoms are acid reflux, heartburn, stomach pain and bad breath;
2 ) Causes chronic gastritis, the main clinical manifestations include upper abdominal discomfort, dull pain, and sometimes belching, acid reflux, nausea, and vomiting;
2 ) Causes chronic gastritis, the main clinical manifestations include upper abdominal discomfort, dull pain, and sometimes belching, acid reflux, nausea, and vomiting;3 ) It may cause gastric mucosal damage, the occurrence of clinical diseases is diverse, and patients often experience acid reflux, belching, fullness, etc.
3 ) It may cause gastric mucosal damage, the occurrence of clinical diseases is diverse, and patients often experience acid reflux, belching, fullness, etc.
These symptoms are also gastritis, ulcers, and ulcers caused by Helicobacter pylori infection.
Picture: Diseases caused by Helicobacter pylori infection .
As early as 1994 Nian WHO IARC under the ( International's Agency for Cancer Research, ON ) on Helicobacter pylori is defined as I carcinogen category
What are the screening methods for Helicobacter pylori? What are the screening methods for Helicobacter pylori?
For the general asymptomatic population, often not recommended for routine testing, but need to rule out the alarm symptoms and family history of gastric cancer, and reduce the age threshold to 35 years of age can significantly reduce the missed digest risks tract tumors
For the general asymptomatic population, often not recommended for routine testing, but need to rule out the alarm symptoms and family history of gastric cancer, and reduce the age threshold to 35 years of age can significantly reduce the missed digest risks tract tumors
For those who suffer long-term symptoms of distress, you should be tested to confirm whether suffering from gastritis, digestive ulcers, and even stomach cancer
Invasive examinations include endoscopy, which can check for any abnormalities in the upper gastrointestinal tract and remove tissue samples
Invasive examinations include endoscopy, which can check for any abnormalities in the upper gastrointestinal tract and remove tissue samples
Specific tests and procedures include:
Serological examination
Serological examination
.
Mainly applicable to epidemiological investigation, with pepsinogen and gastrin -17 simultaneously, more suitable for screening gastric cancer
.
Patients with severe atrophy of the gastric mucosa using other methods may lead to false negatives, and serological testing is not affected by these factors
.
However, breath and stool tests are more suitable than blood tests to detect active Helicobacter pylori infection
.
Breath test
.
The subject generally swallows pills and liquids containing labeled carbon molecules.
If they are infected with Helicobacter pylori, the solution will decompose and release carbon molecules in the stomach, which will be detected by special equipment when they breathe out
.
However, it should be noted that one or two weeks before the test, you should stop taking the acid-suppressing drug proton pump inhibitor ( PPI ), bismuth subsalicylate, antibiotics, etc.
, so as not to interfere with the accuracy of the test
.
.
The subject generally swallows pills or liquids containing labeled carbon molecules.
If they are infected with Helicobacter pylori, the solution will decompose and release carbon molecules in the stomach, which will be detected by special equipment when they breathe out
.
However, it should be noted that one or two weeks before the test, you should stop taking the acid-suppressing drug proton pump inhibitor ( PPI ), bismuth subsalicylate, antibiotics, etc.
, so as not to interfere with the accuracy of the test
.
antibiotic
Stool test
.
The infection is determined by looking for foreign proteins (antigens) related to Helicobacter pylori infection in the stool
.
As with the breath test, PPI and bismuth subsalicylate may affect the test results, so stop taking it before the test
.
.
The infection is determined by looking for foreign proteins (antigens) related to Helicobacter pylori infection in the stool
.
As with the breath test, PPI and bismuth subsalicylate may affect the test results, so stop taking it before the test
.
Endoscopy
.
The endoscope can view any abnormalities of the upper digestive tract and take out tissue samples (biopsy).
It can be used for the diagnosis or differential diagnosis of Helicobacter pylori infection , but it is more invasive
.
The most accurate method is to perform histological examination of the gastric mucosa obtained from two different parts, combined with a rapid urease test or microbial culture
.
.
The endoscope can view any abnormalities of the upper digestive tract and take out tissue samples (biopsy).
It can be used for the diagnosis or differential diagnosis of Helicobacter pylori infection , but it is more invasive
.
The most accurate method is to perform histological examination of the gastric mucosa obtained from two different parts, combined with a rapid urease test or microbial culture
.
diagnosis
What are the treatment methods to eradicate Helicobacter pylori?
What are the treatment methods to eradicate Helicobacter pylori? What are the treatment methods to eradicate Helicobacter pylori?A number of studies have shown that the treatment of Helicobacter pylori can reduce the risk of gastric cancer in infected people
.
A number of studies have shown that eradication of Helicobacter pylori can improve gastric mucosal inflammation, prevent or delay gastric mucosal atrophy and intestinal metaplasia, and can reverse atrophy, but it is difficult to reverse intestinal metaplasia
.
Eradication of Helicobacter pylori before gastric atrophy or intestinal metaplasia can almost completely eliminate the risk of gastric cancer
.
Therefore, after confirmation of Helicobacter pylori infection, standardized treatment is required
.
.
A number of studies have shown that eradication of Helicobacter pylori can improve gastric mucosal inflammation, prevent or delay gastric mucosal atrophy and intestinal metaplasia, and can reverse atrophy, but it is difficult to reverse intestinal metaplasia
.
Eradication of Helicobacter pylori before gastric atrophy or intestinal metaplasia can almost completely eliminate the risk of gastric cancer
.
Therefore, after confirmation of Helicobacter pylori infection, standardized treatment is required
.
At present, the main radical cure programs include " triple therapy " and " quadruple therapy "
.
.
" Triple therapy " is PPI (such as omeprazole, esomeprazole, lansoprazole, pantoprazole, etc.
) plus two antibiotics, such as omeprazole combined with clarithromycin and amoxicillin
.
) plus two antibiotics, such as omeprazole combined with clarithromycin and amoxicillin
.
" Quadruple therapy " , including PPI + bismuth + two antibiotics, the course of treatment is 10 or 14 days
.
.
Because bismuth does not have drug resistance, short-term application safety is high, unless bismuth is contraindicated, China's empirical treatment plan for eradication of Helicobacter pylori recommends the use of bismuth " quadruple therapy " as much as possible
.
.
It is worth noting that the eradication of Helicobacter pylori in patients with gastric mucosal atrophy or intestinal metaplasia can delay the progress of gastric mucosal atrophy and intestinal metaplasia, and can also reduce the risk of gastric cancer to varying degrees
.
2019 China's eradication of H.
pylori and gastric cancer prevention and control expert consensus opinion recommended, the best age for the eradication of Helicobacter pylori in 18 ~ 40 years old
.
.
2019 China's eradication of H.
pylori and gastric cancer prevention and control expert consensus opinion recommended, the best age for the eradication of Helicobacter pylori in 18 ~ 40 years old
.
Of course, the Helicobacter pylori vaccine is an important measure to prevent Helicobacter pylori infection
.
However, due to the complexity of antigen preparation and body response, it is still in the laboratory and clinical research and development stage.
Although certain research progress has been made, it cannot be used in clinical practice in the short term
.
.
However, due to the complexity of antigen preparation and body response, it is still in the laboratory and clinical research and development stage.
Although certain research progress has been made, it cannot be used in clinical practice in the short term
.
In summary, Helicobacter pylori is not terrible and is considered to be one of the important controllable factors affecting the occurrence of the disease
.
In daily life, Helicobacter pylori is mainly transmitted through oral - oral or fecal - oral routes
.
Therefore, in daily life, avoiding the risk factors that cause Helicobacter pylori infection is the most important thing, such as sharing meals with family members or using public chopsticks, prohibiting mouth-feeding children, washing hands before and after meals, and refraining from drinking cold water.
Wait, especially using public chopsticks
.
.
In daily life, Helicobacter pylori is mainly transmitted through oral - oral or fecal - oral routes
.
Therefore, in daily life, avoiding the risk factors that cause Helicobacter pylori infection is the most important thing, such as sharing meals with family members or using public chopsticks, prohibiting mouth-feeding children, washing hands before and after meals, and refraining from drinking cold water.
Wait, especially using public chopsticks
.
Gastric cancer risk self-test form, let’s take a look~
Gastric cancer risk self-test form, come and take a test~ Gastric cancer risk self-test form, come and take a test~references
references1.
National Digestive Disease Clinical Research Center ( Shanghai ), National Alliance of gastrointestinal cancer prevention center (GECA), the Chinese Medical Association of Gastroenterology will pylori study group , and so on .
China eradication of H.
pylori and gastric cancer prevention and control the expert consensus opinion (2019 Nian , Shanghai .
) [J] Chinese Journal of Gastroenterology , 2019, 39 (005): 310-316.
National Digestive Disease Clinical Research Center ( Shanghai ), National Alliance of gastrointestinal cancer prevention center (GECA), the Chinese Medical Association of Gastroenterology will pylori study group , and so on .
China eradication of H.
pylori and gastric cancer prevention and control the expert consensus opinion (2019 Nian , Shanghai .
) [J] Chinese Journal of Gastroenterology , 2019, 39 (005): 310-316.
2.
Helicobacter pylori and hematologic diseases.
http:// class="s4">2.
Helicobacter pylori and hematologic diseases.
http:// class="s5"> http:// class="p4">3.
http:// class="s4">3.
http:// 3.
http://
in this message