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    Home > Biochemistry News > Natural Products News > Heliyon: The compound sesaminol in the shell of sesame seeds may prevent the occurrence of Parkinson's disease in the population by activating special signaling pathways!

    Heliyon: The compound sesaminol in the shell of sesame seeds may prevent the occurrence of Parkinson's disease in the population by activating special signaling pathways!

    • Last Update: 2021-03-23
    • Source: Internet
    • Author: User
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    March 8, 2021 // - In a research report published in the international journal Heliyon a few days ago, scientists from Osaka City University and other institutions discovered through research that a compound naturally present in sesame seeds, sesame Sesaminol may protect the body against Parkinson's disease by preventing neurological damage that reduces dopamine production; in vitro experiments researchers have revealed how sesaminol can be processed by regulating the production of reactive oxygen species and the movement of antioxidants Due to the oxidative stress in the body, in vivo experiments, researchers have revealed that dietary intake of sesaminol may increase the production of dopamine in mice and significantly improve the body's motor function.


    Heliyon

    Sesame oil is used by many people because of its fragrance and high ignition point.


    Image source: Akiko Kojima-Yuasa

    Researcher Professor Akiko Kojima-Yuasa said that there is currently no effective strategy to prevent Parkinson's disease.


    The researchers pointed out that they obtained the same results in in vivo experiments.


    Finally, the researcher Kojima-Yuasa said that the first drug to treat Parkinson's disease may be the natural food ingredient sesaminol (a natural “waste” produced by the sesame seed industry).


    Original source:

    Original source:

    Haruka Kaji, Isao Matsui-Yuasa, Kayo Matsumoto, et al.


    Haruka Kaji, Isao Matsui-Yuasa, Kayo Matsumoto, et al.
    Sesaminol prevents Parkinson's disease by activating the Nrf2-ARE signaling pathway , Heliyon (2020).
    DOI:10.
    1016/j.
    heliyon.
    2020.
    e05342 Sesaminol prevents Parkinson's disease by activating the Nrf2-ARE signaling pathway Heliyon
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