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HEMATOLOGY: Clinical features and neurological outcomes of pediatric immune-mediated thrombotic thrombocytopenic purpura: a report from a large pediatric hematology center

 Last Update: 2022-09-30
 Source: Internet
 Author: User

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Thrombotic thrombocytopenic purpura (TTP) is a potentially life-threatening disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, ADAMTS13 (a de-integrin with a platelet-reactive protein 1 repeat, member 13) activity severely reduced or absent, and associated with varying degrees of organ dysfunction
.

A single-center retrospective cohort study conducted immune-mediated TTP (iTTP)
for all children and adolescents attending a children's health center in Atlanta, Georgia, between 2001 and 2021.

Figure 1: Patient's response
to treatment.

Figure 2: Overview of immunomediated thrombotic thrombocytopenic purpura (iTTP): follow-up time, relapse, and comorbidities
.

Original Source:

Graciaa, S, Adeagbo, S, Fong, G, et al.

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