echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > How cancer cell "antenna" affects cancer treatment

    How cancer cell "antenna" affects cancer treatment

    • Last Update: 2020-06-07
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    The scientific community has long been exploring whether activating CD95 can trigger tumor apoptosis or stimulate tumor cell growthOn this basis, the researchers explored how to control CD95 with drugs that could trigger tumor apoptosisprevious studies have found that activating CD95 triggers their apoptosis mechanism strains for tumor cells isolated from pancreatic tumors and glioblastoma slices in a petri dishThe researchers thought they had found the perfect way to cause tumor cell death and conducted further animal experimentsThey injected CD95 ligands into mice with brain tumors, and the results were unexpected, and instead of shrinking, the tumor accelerated growthto explain the inconsistencies between the two results in petri dishes and animal experiments, researchers at the German Cancer Research Centre and others conducted further research and found that intercellular contact may determine how CD95 worksFor individual tumor cells, activating CD95 causes it to apoptosis, and for tumor cells in tissues, activating CD95 encourages their growthIn other words, even if a tumor cell is in contact with only one cell, activating CD95 does not cause it to apoptosisMartin Villarva of the German Cancer Research Centre, who led the study, said the results could help doctors develop new therapies that convert CD95's growth-stimulating signals to apoptosis signals, and also help prevent tumor cells from becoming resistant to treatmentprevious clinical trialshave shown that blocking CD95 signals can improve survival in patients with glioblastoma when used in combination with radiotherapyMartin Villarva says their study explains the phenomenon for the first time.
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.