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    Home > Medical News > Latest Medical News > How cheap is the new crown vaccine for adenovirus vectors and easy to store?

    How cheap is the new crown vaccine for adenovirus vectors and easy to store?

    • Last Update: 2021-01-02
    • Source: Internet
    • Author: User
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    Figure 1 Media reports that a new coronary vaccine with adenovirus as a carrier in China is highly safe in the development of adenovirus, which obviously play a role in the treatment of cancer Although adenovirus can cause some human respiratory diseases, but it is not a very serious or irrecilable disease, most of which belong to self-limiting diseases, that is, self-healing.
    therefore, adenovirus is less harmful to the human body.
    it can be used to express genes and self-replicate.
    but with a little modification, scientists can make it a replication defect vector, which prevents adenovirus from replicating in the body so that it does not divide into newly divided cells.
    so overall, adenovirus is safe and reliable, and it is recommended as a carrier of gene expression for disease treatment and vaccine development.
    , however, scientists remain overly optimistic about the safety of adenovirus, with reports suggesting that patients who have been genetically treated with adenovirus vectors have died as a result of ineffective treatment.
    so being risky doesn't mean there's no risk in the end, we still need to be vigilant.
    , adenovirus vectors are commonly used in tumor gene therapy.
    are also used in gene therapy and as vaccines for expressing exogenetic antigens.
    adenovirus vector may have replication defects; Some important viral genes are removed and replaced by expression of foreign therapeutic genes.
    these vectors are used in gene therapy, such as vaccines and cancer treatments.
    Generally speaking, cancer gene therapy is used through adenovirus to produce vector products with replicated active anti-tumor cell receptors, which can be copied in cancer cells first and destroy cancer cells from the inside, thereby producing a solute effect.
    Figure 2 Adenovirus vectors for the clinical treatment of prostate cancer have significant clinical effects The effectiveness of the new coronavirus vector vaccine doubts whether the adenovirus vector has been used as a development of other vaccine adenovirus vectors before being used to develop new coronavirus vectors, in fact, this is not the first time that vaccine research and development has been used.
    he had been used to develop vaccines long before the new crown vaccine was developed.
    as early as 2003, Merck developed an HIV vaccine using adenovirus vectors, but eventually found that it was neither effective in preventing HIV infection nor reducing viral load, and even found that the risk of infection in people who were vaccinated increased.
    why? Later studies have found that adenovirus may be too common in the environment.
    The human body has been infected with this adenovirus before, their body will produce immune resistance to the virus, even if they recover, the body will reserve this immune resistance, when we are vaccinated against this virus, there is no waiting for the adenovirus to play a role in a large number of expression of anti-inflammatory proteins.
    immune resistance previously reserved in the body, the body's immune system began to remove the vector vaccine, which weakens its effectiveness.
    , this removal also depletes the body's immunity, reduces external defenses, and may make the body more vulnerable and reduces the risk of infection.
    in short, the body's reserved immune resistance may weaken the effectiveness of the vaccine, reducing the body's defenses.
    the biggest advantage of a small adenovirus vaccine is that it is cheap and easy to store.
    the biggest advantage of the adenovirus vector vaccine is that it's cheap, so why? Because compared to traditional mRNA vaccines, the price is only one-tenth or less of the mRNA vaccine.
    , traditional new vaccines often require transport conditions of minus 20 degrees Celsius, or even minus 70 degrees Celsius, but adenovirus vaccines require as little as 5 degrees Celsius.
    , it's too convenient to keep a vaccine against adenovirus.
    its ultimate effectiveness may be lower than similar vaccines, but due to its price concessions and convenient preservation and transportation, rapid mass production and other functions.
    can be expected to have a huge market for new crown vaccines for adenovirus in developing countries and countries such as Africa.
    , the potential benefits of adenovirus as the basis for new vaccines, as a carrier of genes and cancer treatment, are increasingly being recognized.
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