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Do you know? You are very "hate" small fat meat also has its kind and lovely side! Fat cells will actually actively gather to the wound, to help isolate the external environment, help macrophages clean up cell fragments, local release of antimicrobial peptides, the whole child a wound all-powerful assistant ah! The study, published in the journal Cell," was published in the journal Developmental Cells, from the University of Bristol in the UK.
thanks to advanced imaging technology, so that researchers can solve the biological mystery, but also can bring us a visual feast - not much nonsense, let's start now - first look at what happens after the injury.
white blood cells are worthy of the body's immune pioneers, immediately gathered near the wound! Wait, who seems to be coming in the lower right corner? Oh, there's another emergency response.
is big so it's too late? Or is it a simple pass? After the wound had healed, the mysterious unit retreated and appeared to have come to the rescue.
who the mysterious good-hearted people are? Look at this plump body! Look at this gesture! It's hard!? The scientist had an incredible guess in his mind.
to say that the body meets the characteristics of the body of cells, it is only fat cells, but we all know that fat cells are a "house", let it go out, let alone take the initiative to go out, there is no! These are the phenomena that scientists observed on fruit flies.
you don't look down on it because the fruit fly is a bug, it is also a very important experimental creature with fat meat, in it has completed a lot of scientific research tasks! The fat body of fruit fly can be seen as a combination of vertebrate adipose tissue and liver, this part of the function is quite conservative in evolution, many mechanisms are similar to humans! You see, below is the dynamic map of the fat distribution in the body of fruit flies, green is the body cells, orange is the fat body. how
, little bugs, also did not thin to go - scientists use laser equipment to create a different kind of wound on the fruit fly, ready to study what these small fat meat actually works.
hey - this thing is interesting, you see, after the wound is formed, the fat cells (green) of the abdominal poop will be unusually flexible to rush to the wound, with their own strong body to block the defective epithelial cells (red), wait until the wound heals before leaving.
to be more playful, these fat cells are not fighting alone.
the wound is very small, a fat cell can put the door on the big ah, you have to be the whole family together on the fat cell is looking good heart, come, not come in handy without hurry to go, on the side of the ready to stand by.
, so it's coming over? In general, the body's cells move, are the use of "walking" way.
some cells, ah, with a structure called "pseudo-foot", we call them claws! Generally the cells are stretching their claws, grasping the ground, pulling themselves over, and then stretching their claws, a bit like the feeling of this picture below, understood as rock climbing also become.
but, as soon as the scientists observed, fat cells didn't come so "walking."
does it still have a "car" to sit on? Ride the car is our joke, the scientists are referring to, is not the injury when the blood flow out, by the way the fat cells washed out? Of course not, not much not interesting, in fact, fat cells are really their own initiative to come, just not "go" to come, but, Emmmm, the northeast has a particular image of the word, gu yong.
the left side of the image is a three-dimensional projection, on the right is a floor plan, you can see the fat cells struggling to compress themselves, one by one to strive forward.
scientists knocked out the genes of actin, theoretically without the kinetic protein cells can't move.
, fat cells are really much more honest.
to say this fat cell, really big people never speak up.
it bears all kinds of name-calling, in fact, behind a lot of good things ah.
, for example, came to the wound, it is afraid that their soft body can not block all the gaps, but also to extend the small claws firmly seal edified the wound, blocking the outside of the bad bacteria.
see those green silkc?? Scientists measured the data, these claws left a gap of less than 20nm, a bacteria do not think about the past, is really a husband when the wanfu opened! It's not enough to hold the door, and the wound will leave debris around those broken cells.
so fat cells crowded ah, the debris are squeezed to the edge, convenient for macrophages cleaning.
, but fat cells after all, fat cells grow fat, slower than blood cells, in case there are bacteria to take advantage of this opportunity to slip into the wound how to do? Afraid! Fat cells will also release antimicrobial peptides at the right time, resisting fast-running troublemakers! Look at fat cells crowding open-blood cells, bravely stopping them in front of the British posture, and a little moved ah - then the scientists decided to expand this discovery to vertebrates, to see if mouse rabbits or even humanbody there is such a magical phenomenon.
I won't lose weight until the next paper comes out anyway! Source: Science Academy.