How the terrifying Ebola virus escapes the body's immune defenses

"The Ebola virus is very good at evading the body's immune defenses.

After the Ebola virus first appeared in Africa in 1976, it caused multiple outbreaks on the African continent.

In their laboratory work-mostly with research partners from CIMUS at the University of Compostela in Santiago, Spain and Bernhard Nocht Institute of Tropical Medicine in Hamburg, Germany-the researchers determined that the interaction with VP24 caused the nuclear membrane to rupture The cell membrane composition

The researchers further showed that VP24 disrupted the signaling pathway that activates the immune system to resist the invasion of viruses such as Ebola

"We believe that the discovery of the new activity of Ebola VP24 protein and its serious damage to infected cells will help promote further research on effective methods to treat and prevent the spread of deadly viruses, perhaps through a new inhibition Agent to achieve," said Dr.

Journal Reference :

Santiago Vidal, Maite Sánchez-Aparicio, Rocío Seoane, Ahmed El Motiam, Emily V.